• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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sonya marshall-gradisnik

  1. C

    Transient receptor potential melastatin 3 dysfunction in post COVID-19 condition and myalgic encephalomyelitis/chronic fatigue… (Sasso et al, 2022)

    Transient receptor potential melastatin 3 dysfunction in post COVID-19 condition and myalgic encephalomyelitis/chronic fatigue syndrome patients Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe multisystemic condition associated with post-infectious...
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    Alteration of Cortical Volume and Thickness in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Thapaliya et al, 2022)

    Authors Kiran Thapaliya, Sonya Marshall-Gradisnik, Donald Staines, Jiasheng Su, Leighton Barnden Abstract Myalgic Encephalomyelitis/Chronic fatigue syndrome (ME/CFS) patients suffer from neurocognitive impairment. In this study, we investigated cortical volumetric and thickness changes in...
  3. Pyrrhus

    Volumetric differences in hippocampal subfields and associations with clinical measures in ME/CFS (Thapaliya et al., 2022)

    Volumetric differences in hippocampal subfields and associations with clinical measures in ME/CFS (Thapaliya et al., 2022) https://onlinelibrary.wiley.com/doi/full/10.1002/jnr.25048 From the team of Dr. Kiran Thapaliya, Leighton Barnden, Donald Staines, and Sonya Marshall-Gradisnik. The...
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    Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyeli...(Eaton-Fitch et al, 2022)

    Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients (Eaton-Fitch et al, 2022) Authors: Natalie Eaton-Fitch Stanley Du Preez Hélène Cabanas Katsuhiko Muraki Donald Staines Sonya...
  5. Pyrrhus

    A systematic review of mitochondrial abnormalities in ME/CFS/SEID (Holden et al., 2020)

    I thought this 2020 meta-analysis from Staines and Marshall-Gradisnik had already been posted, but I must have missed it... A systematic review of mitochondrial abnormalities in ME/CFS/SEID (Holden et al., 2020) https://dx.doi.org/10.1186%2Fs12967-020-02452-3 Excerpt:
  6. Pyrrhus

    IJERPH Special Issue "Chronic Fatigue Syndrome: Medical, Nursing and Public Health Management"

    A special issue of International Journal of Environmental Research and Public Health (IJERPH) "Chronic Fatigue Syndrome: Medical, Nursing and Public Health Management"
  7. Pyrrhus

    ICC vs. Fukuda: Diffusion tensor imaging results differ based on diagnostic criteria (Thapaliya et al., 2021)

    Diffusion tensor imaging reveals neuronal microstructural changes in ME/CFS (Thapaliya et al., 2021) https://onlinelibrary.wiley.com/doi/10.1111/ejn.15413 From Dr. Kiran Thapaliya and Leighton Barnden, along with Donald Staines and Sonya Marshall-Gradisnik. What is Diffusion Tensor Imaging...
  8. Murph

    IL-2 stimulation and treatment of TRPM3 on channel co-localisation with PIP 2 and NK cell function (Marshall-Gradisnik et al 2021)

    The effect of IL-2 stimulation and treatment of TRPM3 on channel co-localisation with PIP 2 and NK cell function in myalgic encephalomyelitis/chronic fatigue syndrome patients Natalie Eaton-Fitch 1 2...
  9. Hufsamor

    Potential therapeutic benefit of Low Dose Naltrexone

    https://www.frontiersin.org/articles/10.3389/fimmu.2021.687806/abstract?fbclid=IwAR1rsFXgvh_FB-IEsMBLuI5b559lIUhyWhXoxWs19gmugwqf2tPD0Fm7lko The discovery of the widely expressed Transient Receptor Potential Melastatin 3 (TRPM3) as a nociceptor channel substantially targeted by certain opioid...
  10. Pyrrhus

    A preliminary investigation of nutritional intake & supplement use in Australians with ME/CFS & implications on health-related quality of life (2021)

    A preliminary investigation of nutritional intake and supplement use in Australians with myalgic encephalomyelitis/chronic fatigue syndrome and the implications on health-related quality of life (Weigel et al., 2021) Breanna Weigel, Natalie Eaton-Fitch, Rachel Passmore, Hélène Cabanas, Donald...
  11. Pyrrhus

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS (Maksoud et al., 2021)

    Another literature review from Staines and Marshall-Gradisnik: A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS (Maksoud et al., 2021) https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4 Excerpt:
  12. leokitten

    A systematic review of neurological impairments in myalgic encephalomyelitis/chronic fatigue syndrome using neuroimaging techniques

    This is a pretty well done and thorough review paper, makes for a good reference to find papers you might've read long ago on particular neuroimaging studies of ME. While most, if not all, the neuroimaging studies in ME had fairly small sample sizes (due to abysmal ME funding!) and most used...
  13. Murph

    Hyperintense sensorimotor T1 spin echo MRI is associated with brainstem abnormality in CFS

    Neuroimage Clin. 2018;20:102-109. doi: 10.1016/j.nicl.2018.07.011. Epub 2018 Jul 11. Hyperintense sensorimotor T1 spin echo MRI is associated with brainstem abnormality in chronic fatigue syndrome. Barnden LR1, Shan ZY2, Staines DR3, Marshall-Gradisnik S4, Finegan K5, Ireland T6, Bhuta S7...
  14. Cheesus

    Decreased connectivity and increased BOLD complexity in the default mode network in individuals with

    Decreased connectivity and increased BOLD complexity in the default mode network in individuals with chronic fatigue syndrome Dr. Zack Y Shan, Mr. Kevin Finegan, Dr. Sandeep Bhuta, Mr. Timothy Ireland, Prof. Donald R Staines, Prof. Sonya M Marshall-Gradisnik, and Dr. Leighton R Barnden. Brain...