Transient receptor potential melastatin 3 dysfunction in post COVID-19 condition and myalgic encephalomyelitis/chronic fatigue syndrome patients
Abstract
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe multisystemic condition associated with post-infectious...
Authors
Kiran Thapaliya, Sonya Marshall-Gradisnik, Donald Staines, Jiasheng Su, Leighton Barnden
Abstract
Myalgic Encephalomyelitis/Chronic fatigue syndrome (ME/CFS) patients suffer from neurocognitive impairment. In this study, we investigated cortical volumetric and thickness changes in...
Volumetric differences in hippocampal subfields and associations with clinical measures in ME/CFS (Thapaliya et al., 2022)
https://onlinelibrary.wiley.com/doi/full/10.1002/jnr.25048
From the team of Dr. Kiran Thapaliya, Leighton Barnden, Donald Staines, and Sonya Marshall-Gradisnik.
The...
Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients (Eaton-Fitch et al, 2022)
Authors:
Natalie Eaton-Fitch
Stanley Du Preez
Hélène Cabanas
Katsuhiko Muraki
Donald Staines
Sonya...
I thought this 2020 meta-analysis from Staines and Marshall-Gradisnik had already been posted, but I must have missed it...
A systematic review of mitochondrial abnormalities in ME/CFS/SEID (Holden et al., 2020)
https://dx.doi.org/10.1186%2Fs12967-020-02452-3
Excerpt:
A special issue of International Journal of Environmental Research and Public Health (IJERPH)
"Chronic Fatigue Syndrome: Medical, Nursing and Public Health Management"
Diffusion tensor imaging reveals neuronal microstructural changes in ME/CFS (Thapaliya et al., 2021)
https://onlinelibrary.wiley.com/doi/10.1111/ejn.15413
From Dr. Kiran Thapaliya and Leighton Barnden, along with Donald Staines and Sonya Marshall-Gradisnik.
What is Diffusion Tensor Imaging...
The effect of IL-2 stimulation and treatment of TRPM3 on channel co-localisation with PIP 2 and NK cell function in myalgic encephalomyelitis/chronic fatigue syndrome patients
Natalie Eaton-Fitch 1 2...
https://www.frontiersin.org/articles/10.3389/fimmu.2021.687806/abstract?fbclid=IwAR1rsFXgvh_FB-IEsMBLuI5b559lIUhyWhXoxWs19gmugwqf2tPD0Fm7lko
The discovery of the widely expressed Transient Receptor Potential Melastatin 3 (TRPM3) as a nociceptor channel substantially targeted by certain opioid...
A preliminary investigation of nutritional intake and supplement use in Australians with myalgic encephalomyelitis/chronic fatigue syndrome and the implications on health-related quality of life (Weigel et al., 2021)
Breanna Weigel, Natalie Eaton-Fitch, Rachel Passmore, Hélène Cabanas, Donald...
Another literature review from Staines and Marshall-Gradisnik:
A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS (Maksoud et al., 2021)
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4
Excerpt:
This is a pretty well done and thorough review paper, makes for a good reference to find papers you might've read long ago on particular neuroimaging studies of ME.
While most, if not all, the neuroimaging studies in ME had fairly small sample sizes (due to abysmal ME funding!) and most used...
Decreased connectivity and increased BOLD complexity in the default mode network in individuals with chronic fatigue syndrome
Dr. Zack Y Shan, Mr. Kevin Finegan, Dr. Sandeep Bhuta, Mr. Timothy Ireland, Prof. Donald R Staines, Prof. Sonya M Marshall-Gradisnik, and Dr. Leighton R Barnden. Brain...