• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. SWAlexander

    A Potential Blood Test for Chronic Fatigue Syndrome (ME/CFS)?

    Over two years ago I suggested that research should pay attention to hormones, regarding energy levels (cortisol and serotonin). Endocrinology must be involved in research. Nothing in the body can function without the hypothalamic/adrenal system. "The authors asserted that it “is crucial to...
  2. Joel98

    Can I try 5-HTP despite the possible Metabolic Trap without irreversibly worsening it?!

    Hello, I'm wondering if I can test 5-HTP capsules without worsening the possible Metabolic Trap. If I understand it correctly, it is still unclear whether you have too much or too little serotonin as a result. My symptoms tend to feel like too little and a urine test (which I know has little...
  3. C

    Too Much Serotonin

    So I am pretty sure that I have a major problem with too much serotonin. I have almost every symptom of serotonin syndrome. It seems to go into overdrive with any stressor of any type. When I crash from exertion or get triggered by a stressor, my neck and face get red. My muscles tense...
  4. nerd

    Severe COVID-19: A serotonine-mediated disease

    I found this research from Dr. Farid Jalali, and it finally explains why severe COVID-19 is so severe despite antivirals and immune suppressants. It's all driven by serotonin from destroyed platelets. I'm mentioning this because it can also explain the damage to the Blood-Brain Barrier (BBB)...