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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. GreenEdge

    Carbohydrate-Insulin Model of Obesity: Beyond ‘Calories In, Calories Out’

    The evidence as I see it: Type 1 diabetes - in this condition, the pancreas makes little or no insulin. Before the invention of synthetic human insulin in 1978, this was a fatal condition due to chronic hyperglycemia (high blood glucose) causes β-cell defects by the excess accumulation of...
  2. X

    Balooning Waist size Help

    Hi forum members, sometime back I had posted on how its been increasingly difficult for me to loose weight being hypothyroid. Well I did manage to loose around 7-8 kgs since than. I was around 106kgs for my 189cms height, and I am currently 98-99kgs. The one main change I made was cutting off...
  3. SNT Gatchaman

    Going Back to the Biology of FGF21: New Insights (Lewis et al, 2019)

    Going Back to the Biology of FGF21: New Insights Jo E. Lewis, Francis J.P. Ebling, Ricardo J. Samms, Kostas Tsintzas Fibroblast growth factor 21 (FGF21) is a protein highly synthesized in the liver that exerts paracrine and endocrine control of many aspects of energy homeostasis in multiple...
  4. Hip

    Fecal microbiota transplantation (FMT) fails to improve obesity, study finds

    Obesity is linked to higher intestinal levels of certain Firmicutes bacteria in relation to Bacteroidetes bacteria. Overweight individuals tend have more Firmicutes bacteria in their gut, whereas normal weight individuals tend have more Bacteroidetes bacteria. Ref: 1 This perhaps suggests the...