Pre print Approved: 12 December 2023
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a frequent, debilitating and still enigmatic disease. There is a broad overlap in the symptomatology of ME/CFS and the Post-COVID Syndrome (PCS). A fraction of the PCS patients develops the full...
capillary ischemia-reperfusion
dysfunction by inducing sodium- and calcium-overload in skeletal muscles
endothelial dysfunctionmitochondrialdysfunction
Published: 14 December 2022
Abstract
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease that lacks known pathogenesis, distinctive diagnostic criteria, and effective treatment options. Understanding the genetic (and other) risk factors...
Around 1 month before the onset of my ME/CFS I had an organic acids analysis done. I wondered if anyone here could point to anything that's relevant to ME/CFS. Again, I was feeling unwell at this point but definitely did not have M.E. My cfs wasn't caused by viral onset as far as I know, so I...
The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function
Cara Tomas ,
Joanna L. Elson,
Victoria Strassheim,
Julia L. Newton,
Mark Walker
Published: April 10, 2020...
Here's new treatment potential for mitochondrial dysfunction
...and more, using the mangosteen fruit pericarp:
Front. Psychiatry, 13 March 2019
https://doi.org/10.3389/fpsyt.2019.00115
The Therapeutic Potential of Mangosteen Pericarp as an Adjunctive Therapy...
Four independent ME/CFS research groups have now found "something in the serum" of ME/CFS patients which adversely affects the energy metabolism of healthy cells in vitro, when those cells are exposed a drop of ME/CFS patients' blood serum.
(1) Fluge and Mella in 2016 showed that when myoblast...