• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To register, simply click the Register button at the top right.

mast cells

  1. T

    Activated charcoal, bentonite clay, Zeolite binders

    Just realized a whole lot of my issues come from Mast Cell activation and endotoxins. Ive been doing the carrots but I think I need the big guns. So far Activated charcoal has been working to mop up a lot of die off symptoms from eradication of gut bacteria. The die off is very severe and the...
  2. T

    Quercetin metabolism, sulphur

    Hi all! I’m very confused and hope someone can help me. I really would like to take Quercetin for my MCAS but I also have hydrogen sulfide Sibo which causes sulfur intolerance. There’s conflicting information regarding quercetin becoming metabolite of sulphur in the body. When I message...
  3. nerd

    Poll: Mast cell and histamine degradation genotypes

    I know that there has been one poll on how frequently MCAS co-exists with CFS/ME. But I could imagine that some of the negative cases just are not perceived as MCAS when, in fact, the mast cells might still be dysregulated asymptomatically. This is why I would prefer to describe the condition...
  4. L

    An Inflammation-Centric View of Neurological Disease: Beyond the Neuron (2018) Skaper et al

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871676/ Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a normally beneficial acute inflammatory response, chronic...
  5. J

    Losing Progress, Looking for Next Step

    I've been dealing with health issues the past 6-7 years and while making some serious headway, I've recently started to backslide and am not quite sure of my next step. I'm starting to feel like I'm entering the final phase of my ability to manage symptoms and looking for a helping hand in...