kynurenine

  1. nerd

    Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls

    Groven N, Reitan SK, Fors EA, Guzey IC. Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls. Psychoneuroendocrinology. 2021 Sep;131:105287. doi: 10.1016/j.psyneuen.2021.105287. Epub 2021 May 27. PMID: 34090138. Abstract
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    • fibromyalgia https://forums.phoenixrising.me/attachments/the_kynurenine_pathway_in_the_cns-png.44686/ ido metabolic trap kynurenine neurotoxicity
    • Replies: 5
    • Forum: Latest ME/CFS Research
  2. nerd

    Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms

    Vancassel S, Capuron L and Castanon N (2018) Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms. Front. Neurosci. 12:499. doi: 10.3389/fnins.2018.00499 Abstract How is this relevant? One of the unsolved questions of...
  3. A

    Is excitotoxicity essentially mean high anxiety levels?

    In the model of GR resistance and low TDO, the body has more tryptophan reserve for serotonin and also for IDO(as a compensating mechanism?). What I mean is, what if a person has got high levels of Kynurenine pathway metabolites such as Kynurenic acid and quinolonic acid, what would be the final...
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