Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Ursodeoxycholic acid

Discussion in 'Other Health News and Research' started by RYO, Sep 3, 2018.

  1. RYO

    RYO Senior Member

    Existing liver drug can help treat Alzheimer's (

    "How does UDCA impact mitochondria?
    The authors also noticed that the drug improves mitochondrial function by "correcting" the shape of the affected mitochondria.

    UDCA does this by redistributing a protein called "Dynamin-related protein 1" (Drp1). Drp1 plays a key role in supporting the healthy dynamics of mitochondria, and the scientists believe that it may ultimately protect against neurodegeneration."

    From Wikipedia -
    "UDCA, from Latin noun ursus meaning bear, as bear bile contains the substance, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria."

    Could UDSA have therapeutic benefits for ME/CFS patients?

    Could microbiome dysbiosis in ME/CFS patients lead to lower levels intrinsic UDSA levels?

    Is ME/CFS a neurodegenerative disorder triggered by mitochondrial dysfunction?
    Last edited: Sep 8, 2018
    pattismith and S-VV like this.

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