Things that Raise/Homocysteien

[rydra_wong]

I just ran across another study showing that comething in coffee and tea raise homocysteine (translate dysregulate your methylation: http://www.ajcn.org/content/73/3/532.short

I thought I would invite comment. On a former memory stick that was stolen I had gathered some studies on coffee and tea regarding methylation and it seemed to show that coffee raises homocysteine but tea (overall) decreases it, although when tested by component, there are component(s) in tea that raise it.
However I found studies that showed tea causes neural tube defects in pregnant woman and that showed the reason it is stronger than any chemo on the market is because it breaks folate metabolism (something I do not want). I used to drink a lot of tea and stopped for this very reason. Tea has me puzzled because so many healthy people drink it and tout its health benefits.

On WrongDiagnosis a list of things that affect methylation was posted. I thought I'd repost here and see if anyone has any more to add.

These food items could be a reason for crashes and the like so it seems a good idea to keep them in mind:

Oh, I could not find that list so I guess I'll start a new one:

Things that raise homocysteine:

The drugs are from these two websites:
http://www.drmirkin.com/heart/1042.html
http://www.lef.org/magazine/mag2009/aug2009_Is-Homocysteine-Making-You-Sick_02.htm

Azaribine
Caffeine
Cholestyramine
Colestipol
Colchicine
Fenofibrate
Levadopa
Metformin
Methotrexate
Niacin
Nitrous oxide
Non-steroidal anti-inflammatory drugs (NSAIDs)
Pemetrexed
Phenytoin
Pyrimethamine
Sulfasalazine

tea - http://jn.nutrition.org/content/137/1/223S.short (DNA hypomethylation)
[Tea drinking (green or black) significantly lowers breast cancer rates (40-60%) in COMT+/+ and COMT+/+ but not in COMT-/- - due to catechol-containing poly[henols using up SAMe (so cancer cant grow but neither can you?) - http://cancerres.aacrjournals.org/content/63/21/7526.full ]
insulin - http://www.ncbi.nlm.nih.gov/pubmed/10470367
reduced kidney function - http://care.diabetesjournals.org/content/24/3/533.short
smoke
red wine, liquor, but not beer - http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)74186-6/fulltext
red wine, liquor, OR beer - http://alcalc.oxfordjournals.org/content/36/3/189.short
red wine, but beer lowers - http://www.ajcn.org/content/78/2/334.full.pdf+html
Quercetin - http://www.sciencedirect.com/science/article/pii/S0009912005003073
Catechol-containing polyphenols use up SAMe, causing DNA hypomethylation - http://jn.nutrition.org/content/137/1/223S.full





Things that lower homocysteine:


estrogen - http://cardiovascres.oxfordjournals.org/content/53/3/577.full.pdf+html
http://www.sciencedirect.com/science/article/pii/S0021915099003214
http://www.ncbi.nlm.nih.gov/pubmed/17877128
High folate foods such as spinach, broccoli and lettuce, , asparagus, fruits (bananas, melons, lemons), legumes, yeast, mushrooms, organ meat (beef liver, kidney), orange juice. http://www.mayoclinic.com/health/folate/NS_patient-folate
Vegetables and Citrus (diets high in folate) - http://jn.nutrition.org/content/129/6/1135.short
soy foods - http://www.ajcn.org/content/76/2/365.short
Not soy - http://jn.nutrition.org/content/136/1/100.short
Honey - http://online.liebertpub.com/doi/abs/10.1089/109662004322984789
Beer (even nonalcoholic) due to polyphenol content - http://pubs.acs.org/doi/abs/10.1021/jf048146v
Oleuropein (Olive Leaf Extract, extra virgin olive oil) - http://jn.nutrition.org/content/138/1/36.short


sorry - I ran out of time...

 

[greenshots]

I appreciate this list since I know our Homocysteine levels have been intermittently high too.
Thanks, Rydra!
Angela