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The energy generators inside our cells reach a sizzling 50°C

Discussion in 'Other Health News and Research' started by AndyPR, May 4, 2017.

  1. AndyPR

    AndyPR Senior Member

    Would be interesting to see patients mitochondria tested in this way.
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  2. antherder

    antherder Senior Member

    Sure would. Maybe our mito heaters just aren't working properly. Thanks for posting. Intriguing article.
  3. ZeroGravitas


    Absolutely, although it would pressumably be prohibitively difficult, given that we've only just had the first ever lab measurements (and the tempurature resolution of the dyes is either over 6°C or 10°C).

    Pressumbly our mitochondria are running cooler (if their energy production is at a steady level, rather than pulsed or something), given the "Elevated Energy Production" finding [1,2] - when CFS cells were taken out of patient serrum. The assumption is that the generation capacity is there, structurally, but under-used.

    Naviaux has written quite a bit about the thermodynamics of mitochondria already, right? (Seem to remember, when background reading.) Anything particually pertinent (or confirmed/contradicted) there?

    It's kind of reassuring, encouraging, to see such a big change in understanding here; that science is honing in on the function of this cellular organells that we've been pointing at for a while, finding that we really didn't know them at all well, considering their (increasingly recognised) importance.
    Last edited: May 4, 2017
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  4. Deltrus

    Deltrus Senior Member

    I doubt our mitochondria are running cold because they are the source of the heat in our body. If they were cold then we would be cold.

    Make me wonder however, how hot do they get during fever?
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  5. Deepwater

    Deepwater Senior Member

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  6. AndyPR

    AndyPR Senior Member

    Yep, I agree with @Deepwater , I notice the cold far more than other people I know. Is that down to my mitochondria, I have no idea, but it seems to me, at the very least, a potentially interesting test to run on patients.
  7. Forbin

    Forbin Senior Member

    This kind of reminds me of something I noticed a few months prior to the post-infectious onset of ME.

    For many years, I'd been getting together with friends across town at least a couple of times a month. I'd generally leave fairly late, like at 1:00 AM. It was usually cold outside at that hour, but it never bothered me. In the months prior to coming down with ME, however, when I got in my car I would become wracked with odd chills for several minutes. It was so consistent, and the chills were so "violent," that I wondered what the hell was going on. This odd sensitivity to cold continued right up until the onset of ME.

    I don't know if this had anything to do with ME, my metabolism or mitochondria. If it did, though, it suggests some process that precedes infectious onset, with the infection being more of a tipping point than a sole "trigger."
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  8. sue la-la

    sue la-la

    Melbourne, Australia
    same here - ridiculous sensitivity to the cold, for a few years before ME hit me.
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