Our Newly Ill Face Their First Holiday Season with ME/CFS
Don't look now! The holiday season is on its way. I've lived through decades of them with ME/CFS. So have many of you in our chronically ill community. That's beyond sad for all of us. But at least we have some idea what we're contending with, and have learned our ways of handling...
Discuss the article on the Forums.

Retrovirus Replication Inhibited by Glutathione

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by caledonia, Nov 15, 2009.

  1. Here is a paper talking about HIV replication being inhibited by raising glutathione levels. They discuss a therapy of delivering glutathione to microphages.

    http://jac.oxfordjournals.org/cgi/content/full/52/4/551

    "In AIDS patients, chronic inflammation and elevated levels of cytokines seem to be associated with lower levels of GSH: GSH levels decrease rapidly upon infection with HIV and continue to decline as the disease progresses. Investigators have shown that agents that increase intracellular levels of GSH inhibit HIV replication."

    It seems to me that this would have implications for XMRV and would explain (assuming you were XMRV +):
    a) why we have low glutathione
    b) why the methylation protocol (which raises glutathione) works as a treatment

    And also gives another method of raising glutathione, which might be another possible treatment.
     
  2. anne_likes_red

    anne_likes_red Senior Member

    Messages:
    984
    Likes:
    689
    Most interesting!

    Thanks for posting that link.
     
  3. jayneglow

    jayneglow

    Messages:
    2
    Likes:
    0
    There are other studies involving untreated disease with glutathione cant find the link though, but this is great thanks for the link. :D
     
  4. richvank

    richvank Senior Member

    Messages:
    2,716
    Likes:
    915
    Hi, Caledonia.

    I think you're right about this. It sounds as though, from what I'm hearing from other researchers, that methylation itself will help to silence the expression of the retroviral genes, too, so this treatment might be effective against retroviruses in more than one way. And it does a whole lot of other good things for the metabolism, too, as I've described in my papers http://www.aboutmecfs.org/Trt/TrtGSHIntro.aspx.

    Best regards,

    Rich
     

See more popular forum discussions.

Share This Page