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Overmethylation or paradoxical folate defficiency?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Gondwanaland, Apr 14, 2014.

  1. Gondwanaland

    Gondwanaland Senior Member

    On January 23 I sarted taking 500mcg mB12 (it felt awesome for a week, then it seemed like back to normal).

    On March 9 I started 200mcg methylfolate and was taking 1000mcg mB12 (felt no changes).

    On March 14 I upped my folate to 2 quarters of a tablet (400mcg)

    On March 15 by mistake I took 2 halves (800mcg) of folate

    On March 16 I started feeling a tight chest, breathing difficulty - put ginger on my pumpkin soup with meat and felt greatly relieved, so I started taking ginger tea daily (isn’t helping much anymore – makes my mouth even more dry)

    On March 17 I stopped the folate

    On March 21 I stopped the mB12

    Recent blood results
    Homocysteine (female range 4.44-13.56) before my accident with folate was 6.78 on Feb 7
    on Mar 21 it is 9.81
    Folic acid (3-17.5) 12.6 on Mar 19
    Vitamin B12 872 on Mar 19

    I am having flu like symptoms, anxiety, can't sleep, chills, weakness. It seems that shallow breathing is slowly resolving

    Am I overmethylating or in a paradoxical folate defficiency?

  2. Phred

    Phred Senior Member

    The March 16 symptoms sound like hypokalemia (low potassium) while the present symptoms sound like folate deficiency.

    I get that tight feeling in my chest and take potassium. I really should be taking potassium long before that tightness starts, but I can be stubborn. But as soon as I feel that tightness I get potassium in me right away. Low potassium affecting the heart can be dangerous.
  3. Gondwanaland

    Gondwanaland Senior Member

    Thanks, @Phred
    I have an unpleasant endocrine reaction to KCl, I think it antagonizes my thyroid/adrenals and I get brain fogged, cold hands and feet and chills.

    I tried no flush niacin and niacin with no success in the past weeks. So today I finally overcame my fear (I am unsure at self testing) and took 125mcg mB12 and feel 50% better now...

    It seems the hypokalemia had given place to lack of methyl factors when I interrupted supplementation (UNDERmethylation)... I was too scared and brain fogged to understand...

    I finally found a rheumatologist in my town who prescribes methylation and LDN and accepts my insurance, but could not get an appointment before late May. So now I have to wait 5 weeks for medical help. While things are bearable I will not add folate and will keep the mB12, increasing when needed up to 500mcg.


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