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Is artemisinin + iron effective treatment for CFS?

Discussion in 'General ME/CFS Discussion' started by sorin, May 10, 2018.

  1. sorin

    sorin Senior Member

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    Hello again!

    Anyone here tried Artemisinin (extract of sweet wormwood) + iron? Recent studies show that this combination would be effective in treating cancer and against EBV, HSV, etc.
    I am going to start taking this one https://www.amazon.com/Doctors-Best...000OSYFA4/ref=cm_cr_arp_d_product_top?ie=UTF8 together with Iron Citrate https://www.swansonvitamins.com/swanson-premium-iron-citrate-25-mg-60-veg-caps
    I am thinking to start taking 2 pills (2 x100 mg) artemisinin and 1 Iron citrate (25 mg) per day.
    Did you exeprience any side effects?

    Best regards,
    Sorin
     
    Last edited: May 10, 2018
    Lisa108 likes this.
  2. nanonug

    nanonug Senior Member

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    I doubt it.

    Unless you are have an active parasitic infection, I don't see artemisinin doing much. Regarding iron, unless you are deficient in it, I also don't see how it would help. Iron would probably make you much worse if taken in excessive quantities.

    Could you provide references? Thanks!
     
  3. sorin

    sorin Senior Member

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  4. Lisa108

    Lisa108

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    Artemisia annua is definitely something I'll try in the future. I'm planning to buy dried leaves ("tea") from a German manufacturer, who also educates people in malaria infested countries how to grow and use it.
     
  5. Ravn

    Ravn Senior Member

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    Be really careful with iron: too much is toxic so only ever supplement it if you have tested positive for a deficiency. Even people who don't eat meat can have excessive iron if they have the haemochromatosis mutation for example. So don't just guess, get tested.

    Anecdotally there seem to be PwME who are iron deficient and who therefore may benefit from increasing iron intake or supplementing. BUT there are also PwME with high iron – and that doesn't help their ME one bit.
     
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  6. Hip

    Hip Senior Member

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    It's the semi-synthetic derivative of artemisinin called artesunate that has been used in ME/CFS. It can be bought here.

    Artesunate is around 10 times more potent than artemisinin for fighting cytomegalovirus — see here.

    Dr Paul Cheney said he found artesunate had benefits for ME/CFS, although I don't think there have been any studies on this. And I have not come across any accounts on this forum where someone had major benefits from artesunate. So you would probably be better off using Valtrex or Valcyte for herpesviruses.

    Some more info here and here: Artesunate - Cheney dosage and benefits.
     
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  7. Hip

    Hip Senior Member

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    Apparently iron enhances the antiviral effect of artesunate against cytomegalovirus. See here.

    Although from some pharmacokinetic calculations I did a while ago, I think artesunate is a weak antiviral for cytomegalovirus, even with iron; but artesunate may have some immunomodulatory action against this virus also, which may make it a little more effective.
     
  8. Runner5

    Runner5 Senior Member

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    PNW
    Iron supplements give me really bad constipation.
     
  9. Tammy

    Tammy Senior Member

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    If you suspect you have a virus, I would NOT take an iron supplement. Viruses feed off iron.
     
  10. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    Artesunate is also used to treat a lyme coinfection babesia and probably other bacterial infections??
    Long term use may cause anemia so it might be good to cycle off and on eg 2 weeks on and 2 weeks off??? Or get regular blood work to keep an eye on your red blood cell count.
     
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  11. nanonug

    nanonug Senior Member

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    Thanks, that's the kind of reference I was looking for. I remain skeptical about the use of iron in any "anti-bug" regimen, though, considering how iron tends not only to enhance the replication of all kinds of pathigens but also leads to a great deal of oxidative stress.
     
    Hip likes this.
  12. sorin

    sorin Senior Member

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    What I understood about artemisinin is that it targets the cells that retain iron (such as the cancer cells). When artemisinin is taken together with iron, it becomes more effective than without iron, probably because the extra iron is retained by the tumoral cells and the artemisinin is able to find these cells easier.
     
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  13. Tammy

    Tammy Senior Member

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    Interesting.
     

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