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How to know whether it's low B12, too much B12 or healing?

boo85

Senior Member
Messages
178
How do you know whether the symptoms you are having is caused by too little B12 in your body?

Or whether it's too much B12/methylfolate causing "all systems are go" franticness?

Or even if it's overwhelming healing going on?

How can you tell the difference between the 3 situations?

Thank you!
 

PeterPositive

Senior Member
Messages
1,426
If you follow a "low and slow" approach and add one supplement at a time you should be able to test each ingredient and see how they affect your current situation.

Typically you should start with B12, then add methylfolate and after some time he other cofactors (e.g. B complex, minerals, carnitine, etc...)

Given your COMT V158M +/+ you should probably titrate the folate slowly and monitor possible side effects. On the other hand you don't have any MTHFR mutations so you probably don't need so much folate. Just a tiny bit (100-200mcg) to help your B12.

Did you investigate your methylation status? Serum homocysteine? MMA? Maybe a full methylation panel? That might help understand if and where there is a blockage.

cheers