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Cells coming back on during methylation

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Bdeep86, Dec 6, 2013.

  1. Bdeep86

    Bdeep86 Senior Member

    Hey guys I have seen Freddd mention a couple times when cells and mitochondria start working again they can deplete potassium. Does anyone else know if sodium and magnesium or any other things may become depleted?
  2. helen1

    helen1 Senior Member

    Folate or/and potassium are the two that very commonly get depleted with methylation. Zinc, magnesium, vit D and vit B6 can also get depleted.
  3. stridor

    stridor Senior Member

    Powassan, Ontario
    For me it was B2 that became depleted. The first time my tongue got swollen and cracked. The second it was angular cheilitis, angry capplilaries encircling my pupils, and rash on my jawline, nose and weiner :). TMI? brad
  4. SJB944

    SJB944 Senior Member


    Did taking B2 fix this? If so how much?

  5. Freddd

    Freddd Senior Member

    Salt Lake City
    Hi Bdeep,

    Sodium appears unaffected. Magnesium can be a limiting factor and deadlock b12. I don't know how much a person might need. I take a separate magnesium supplement. All of the vitamins may be come depleted if intake isn't enough. The thing is that makes potassium unique is that it is the most used mineral in the human body. I do know that magnesium is a very popular discussion item and has a lot of effects for a lot of us here.

    L-methylfolate is the other number one item for healing onset insufficiency since it turns on and off by layers. Good luck.

    Here is the latest update of this list.

    Version 1.2 12/08/2013

    Group 1 – Hypokalemia onset. Symptoms may appear with serum potassium as high as 4.3. May become dangerous if ignored. Considered “rare” with CyCbl (cyanocobalamin) it is very common with MeCbl (methylcobalamin) and AdoCbl (adenosylcobalamin) and less so with HyCbl (hydroxycobalamin).

    There does not appear to be a clear order of onset. The order of onset varies widely from person to person but many appear consistent for each episode for any given person. There tend to be more and more intense symptoms as it gets worse. Some people have ended up in the ER because of not recognizing the symptoms.

    IBS – Steady constipation, Nausea, Vomiting, Paralyzed Ileum,

    Hard knots of muscle, Sudden muscle spasms when relaxed, Sudden muscle spasms when stretching , Sudden muscle spasms when kneeling, Sudden muscle spasms when reaching , Sudden muscle spasms when turning upper body to side, Tightening of muscles, spasms and excruciating pain in neck muscles, waking up screaming in pain from muscle spasms in legs. Muscle weakness

    Abnormal heart rhythms (dysrhythmias), increased pulse rate, increased blood pressure
    Emotional changes and/or instability, dermal or sub-dermal Itching, and if not treated potentially paralysis and death.

    Group 2a - Both

    IBS – Diarrhea alternating with constipation, IBS – Normal alternating with constipation

    Group 2b – Either or both

    Headache, Increased malaise, Fatigue

    Group 3 - Induced and/or Paradoxical Folate deficiency or insufficiency

    These symptoms appear in 2 forms generally, the milder symptoms that start with partial methylation block and the more severe symptoms that come on as partial methylation block gets worse or very quickly with methyltrap onset.

    Edema - An additional thing I would like to mention. I would never have found it without 5 years of watching the onset of paradoxical folate insufficiency and trying to catch it earlier and earlier and to figure out what was causing it and to reverse it. For me the onset order goes back to the day of onset now with edema. I noticed that within 2 hours of taking sufficient Metafolin I would have a near immediate increase in urine output.

    Old symptoms returning

    Angular Cheilitis, Canker sores,

    Skin rashes, increased acne, Skin peeling around fingernails, Skin cracking and peeling at fingertips,

    Increased hypersensitive responses, Runny nose, Increased allergies, Increased Multiple Chemical Sensitivities, Increased asthma, rapidly increasing Generalized inflammation in body, Increased Inflammation pain in muscles, Increased Inflammation pain in joints, Achy muscles, Flu like symptoms

    IBS – Steady diarrhea, IBS – Diarrhea alternating with normal, Stomach ache, Uneasy digestive tract,

    Coated tongue, Depression, Less sociable, Impaired planning and logic, Brain fog, Low energy, Light headedness, Sluggishness, Increase irritability, Heart palpitations,.

    Longer term, very serious

    Loss of reflexes, Fevers, Forgetfulness, Confusion, Difficulty walking, Behavioral disorders, Dementia, Reduced sense of taste, bleeding easily

    Group 4 - HyCbl onset, degraded MeCbl onset after photolytic breakdown.

    Itchy bumps generally on scalp or face that develops to acne like lesions in a few days from start.
    Last edited: Dec 8, 2013
  6. stridor

    stridor Senior Member

    Powassan, Ontario
    The B2 worked and it is a long story - if you don't mind can you check out the "A B2 Story" thread? My involvement with B2 is long. brad

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