Does anyone know if having a CBS mutation mean bloating when taking something like MSM? Has anyone else tried MSM and experienced weight gain/bloating? I've read accounts here of people feeling bad but I don't feel bad. Except for my new, smaller jeans are about to cut me in two at the waist, that is. I just starting taking it for my hair and skin, and I've bloated up something terrible. Gained five pounds in 2 days, so I know it's all water. It's also a weird time of the month so that could account for some of it. This happens occasionally but not to this extreme. I'm wondering about possible CBS mutation and what symptoms that could cause. I don't know my genetics and don't seem to have a problem with other sulfur compounds like ALA. Anybody got any ideas?