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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Search results

  1. Violeta

    Seeking Recommendations for Vasodilators Effective in Treating ME/CFS

    Thoughts and questions about hypoperfusion, hypertension, vasodilation, vasoconstriction, neurotransmitters, and receptors are hurting my brain this morning.
  2. Violeta

    Seeking Recommendations for Vasodilators Effective in Treating ME/CFS

    Do neurotransmitters have a part in this, and if so, how important are they? Found this: "The neurotransmitters released from the varicosities in the ANS can regulate the vascular tone. Norepinephrine (NE), adenosine triphosphate (ATP) and Neuropeptide Y (NPY) function as vasoconstrictors...
  3. Violeta

    Seeking Recommendations for Vasodilators Effective in Treating ME/CFS

    I will have to check for sweating normally in response to heat. For a long time I know I didn't, and it's horrible because the heat builds up inside of you. I did a course of body soaks and that helped a lot, and I did start to be able to sweat, but I'm going to have to check again when I am out...
  4. Violeta

    Vit. D causing allergies to flareup

    @cristi_b, Vitamin K2 might help you be able to tolerate Vitamin D. Also, K2 can stop mast cell activation,(allergic reaction), similar to the way quercetin stops it... by stopping the entry of Ca+ into the cell. You would probably need a good size dose at first. I actually think the link that...
  5. Violeta

    Seeking Recommendations for Vasodilators Effective in Treating ME/CFS

    I do experience relief from excessive fatigue from taking a shower. Sometimes I am so tired I can hardly even think of taking a shower, but if I can get myself in the shower it really helps. The heat of summer, though, doesn't do the same thing. It actually makes me feel worse. I don't...
  6. Violeta

    Seeking Recommendations for Vasodilators Effective in Treating ME/CFS

    This is another message from his thread on Twitter. I realize this thread isn't about traumatic brain injury, but it's connected to the glutamate/vasodilators, and the whole thing is just so interesting I thought I would post this link, too. https://x.com/lifeanalytics/status/1216609834046492672
  7. Violeta

    Seeking Recommendations for Vasodilators Effective in Treating ME/CFS

    Some info from @mariovitali on Twitter (now named X) on glutamate and vasoconstriction. https://x.com/lifeanalytics/status/1167489506968317952
  8. Violeta

    Dose Lysine increase or lower methylation?

    I accidentally found this about lysine and methylation while reading a study about COVID and ME/CFS. I don't think it means that lysine affects methylation, but methylation somehow affects lysine. I don't understand it, but I do know that lysine helps me, I am prone to shingles, and my...
  9. Violeta

    Long COVID, POTS, and ME/CFS: Lifting the Fog

    Long COVID, POTS, and ME/CFS: Lifting the Fog Patrick Chambers* Department of Pathology, Torrance Memorial Medical Center, Torrance, California https://www.iomcworld.org/open-access/lc-pots-and-mecfs-lifting-the-fog.pdf MTHFR POTS AUTOIMMUNITY METHYLATION and SHINGLES (I thought I had seen a...
  10. Violeta

    Anti-inflammatory Action of Green Tea

    SARS-CoV-2 spike protein mediates host cell infection and cell-cell fusion that causes stabilization of tumor suppressor p53 protein. SARS-CoV-2 spike S2 subunit inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells...
  11. Violeta

    Talking on the phone

    @Dysfunkion, something in your last message made me wonder if you have or ever have had amalgam fillings.
  12. Violeta

    Anti-inflammatory Action of Green Tea

    I wonder if drinking it away from food or at least away from food or supplements that contains iron would solve that issue.
  13. Violeta

    Anti-inflammatory Action of Green Tea

    Epstein–Barr Virus Infection Is Associated with Elevated Hepcidin Levels https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862144/ We found that children IgG positive to EBV antigens (VCA, EBNA1, and EA) presented hepcidin, AGP, and CRP levels higher than uninfected children. Hepcidin and AGP...
  14. Violeta

    Anti-inflammatory Action of Green Tea

    Yes, decaf will have the same antioxidants.
  15. Violeta

    [Case study] CFS/ME remission story severe patient [2008]

    Has anyone tried kefir made from grains? I have read two studies tonight that say that kefir increases IGg, helps heal leaky gut, and can reduce the amount of Gram-negative bacteria in the intestinal lumen, and therefore lower the amount of lipopolysaccharide (LPS). Here's one study...
  16. Violeta

    Anti-inflammatory Action of Green Tea

    Green Tea (Camellia sinensis) Extract Induces p53-Mediated Cytotoxicity and Inhibits Migration of Breast Cancer Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701076/ An increment in p53 and p21 expression stimulated by green tea extract! Wow, you learn something new every day!
  17. Violeta

    Anti-inflammatory Action of Green Tea

    Increased nuclear factor-κB and loss of p53 are key mechanisms in Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) https://pubmed.ncbi.nlm.nih.gov/22951418/ ME/CFS is considered to be a neuro-immune disease. ME/CFS is characterized by activated immuno-inflammatory pathways...
  18. Violeta

    Anti-inflammatory Action of Green Tea

    That study was not written by marketers. Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335565/#:~:text=The name “myalgic encephalomyelitis”...
  19. Violeta

    Anti-inflammatory Action of Green Tea

    A Review of the Role of Green Tea (Camellia sinensis) in Antiphotoaging, Stress Resistance, Neuroprotection, and Autophagy https://pubmed.ncbi.nlm.nih.gov/30813433/ Several in vivo and in vitro studies suggest that green tea supplementation increases the collagen and elastin fiber content, and...
  20. Violeta

    Anti-inflammatory Action of Green Tea

    Most of the results from the human studies indicated the beneficial effects of green tea and tea catechins against inflammatory diseases. The cellular and animal studies also provided evidence for the favorable effects of green tea/EGCG. These results are compatible with our previous findings...
  21. Violeta

    Anti-inflammatory Action of Green Tea

    https://pubmed.ncbi.nlm.nih.gov/27634207/ Tomokazu Ohishi, Shingo Goto, Pervin Monira, Mamoru Isemura 1, Yoriyuki Nakamura 2016 Most of the results from the human studies indicated the beneficial effects of green tea and tea catechins against inflammatory diseases. The cellular and animal...
  22. Violeta

    Microbiome - Butyrate - Inflammation

    I just went to the link you provided above that talks about butyrate and the Chinese herbs. Very interesting. In this study, they found increased butyrate in the brain. I didn't know there was butyrate in the brain. Milk kefir alters fecal microbiota impacting gut and brain health in mice...
  23. Violeta

    Age-Dependent Astroglial Vulnerability to Hypoxia and Glutamate: The Role for Erythropoietin

    Glutamatergic Signaling Along The Microbiota-Gut-Brain Axis https://www.mdpi.com/1422-0067/20/6/1482 Just one thing from this study tonight: Research in this area opens the possibility to target glutamatergic neurotransmission, either pharmacologically or by the use of probiotics producing...
  24. Violeta

    Age-Dependent Astroglial Vulnerability to Hypoxia and Glutamate: The Role for Erythropoietin

    Molecular Mechanisms of Glutamate Toxicity in Parkinson’s Disease https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.585584/full Under pathological conditions, when excessive glutamate is released from the presynaptic membrane or the reuptake function of glutamate is...
  25. Violeta

    Age-Dependent Astroglial Vulnerability to Hypoxia and Glutamate: The Role for Erythropoietin

    Activation of the gut-brain axis by dietary glutamate and physiologic significance in energy homeostasis https://pubmed.ncbi.nlm.nih.gov/19587084/#:~:text=l-Glutamate receptors and their,indirectly by these vagal inputs. l-Glutamate receptors and their cellular transduction molecules have...
  26. Violeta

    Age-Dependent Astroglial Vulnerability to Hypoxia and Glutamate: The Role for Erythropoietin

    I 💙 this study. https://pubmed.ncbi.nlm.nih.gov/24124607/ How many of my symptoms are caused by glutamate and hypoxia. And what came first, the glutamate or the hypoxia?
  27. Violeta

    Complete shift in symptoms from B vitamins

    I found this study about GABA being helpful for GERD while looking into GERD for one of my neices. https://www.gastrojournal.org/article/S0016-5085(00)70408-2/fulltext#:~:text=Conclusions%3A%20In%20normal%20human%20subjects,inhibition%20of%20transient%20LES%20relaxations. I realize that...
  28. Violeta

    anyone know an herb to reduce adrenaline?

    Reishi Reishi's antioxidants neutralize harmful free radicals, reducing cellular damage and potentially calming the stress response system. This lowers cortisol levels, easing stress. Reishi can nourish the heart and thus pull, harmonize, soothe the spirit Shen. Therefore, it can be used in...
  29. Violeta

    SARS-CoV-2 and EBV; the cost of a second mitochondrial “whammy”?

    That was a good idea getting the Paxlovid ahead of time. Your case sounds like it was very severe. I hope you don't rebound, too.
  30. Violeta

    Looking for a good book on endocrinology

    The Schwarzbein Principle. No, it's not a weight loss book. It's a lot of information about the endocrine system and what to do about issues.