I have pretty much all the symptoms of CFS:
http://www.ncbi.nlm.nih.gov/pubmed/25526825
http://www.ncbi.nlm.nih.gov/pubmed/25677654
http://www.ncbi.nlm.nih.gov/pubmed/25848767
GABA can also regulate several hormone systems:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108002/
(lots more stuff on this, I just didn't want to go find them)
It is a real shame that I found something that works but it only works once a month. And it doesn't really decrease the scope of what my issue is, because it has such a wide range of interactions.
Anyone else try phenibut / baclophen and get a good result? Any comments on possible MoA's or alternatives?
- Poor sleep / cycadian rhythm
- Extreme fatigue at all points in the day
- Food sensitivities and crashes
- Sickness type behavior (gravitating to only low energy activities)
- Brain fog
- Irritability, hard time ignoring sounds etc
- Anhedonia
- Fluctuating vision clarity
- Constipation, gas, light amounts of bowel irritation.
- Anxiety
- Muscle pain
- My mind feels perfectly clear, I notice the thousands of simple things that are pleasurable. Rain outside, the smell of my blanket, etc.
- .I don't get pleasure from things that don't take energy to do (laying down and reading, browsing the internet. pretty much everything I normally do)
- I don't act lazy, my body feels smooth and energetic
- I feel like I can easily focus on stuff, like I can 100% ignore things if they aren't relevent and my mind can expand to fit even simple things that I'm thinking about.
- It feels like time slows down, I can notice facial expressions, I can think about the recent past / future clearly. I don't feel like I'm at the bottom of a mental trench.
- This is the strangest thing for me. I could actually get hungry and then eat and then feel energy after eating. That freaked me out, I didn't remember that every happening for me, I guess I forgot. Atm food is just something I use to keep myself from dying.
- My digestion seems to normalize, and some sort of cellular metabolic process also seems to normalize. I poop once daily.
http://www.ncbi.nlm.nih.gov/pubmed/25526825
http://www.ncbi.nlm.nih.gov/pubmed/25677654
http://www.ncbi.nlm.nih.gov/pubmed/25848767
GABA can also regulate several hormone systems:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108002/
(lots more stuff on this, I just didn't want to go find them)
It is a real shame that I found something that works but it only works once a month. And it doesn't really decrease the scope of what my issue is, because it has such a wide range of interactions.
Anyone else try phenibut / baclophen and get a good result? Any comments on possible MoA's or alternatives?