http://sci-hub.tw/http://dx.doi.org/10.1002/tcr.1008
Taxol® (1, paclitaxel), a poly-oxygenated naturally occurring diterpenoid isolated from the bark of the Pacific yew tree (Taxus brevifolia), is currently considered one of the most important drugs in cancer chemotherapy.1–4 Since its initial isolation in 1966 and subsequent structural determination in 1971, a tremendous amount of research focusing on the science and applications of paclitaxel has been performed.
https://patents.google.com/patent/US20060014968A1/en?q=paclitaxel&q=yew&oq=paclitaxel+yew
Paclitaxel is an anticancer compound primarily derived from the bark of the Taxus brevifolia (Pacific yew) tree. In the 1960's, the National Cancer Institute began a study of plant extracts exhibiting anti-cancer or anti-neoplastic activities. The crude extract of bark from the Taxus brevifolia was found to inhibit a variety of tumors. In 1971, paclitaxel was isolated and described by M. C. Wani et al. (J. Am. Chem. Soc. 93, 2325, (1971)), who defined the structure of paclitaxel using chemical methods and X-ray crystallographic analysis. In 1979, Schiff and coworkers demonstrated paclitaxel's novel mechanism of action. This mechanism includes binding to microtubules and preventing their depolymerization under conditions where depolymerization would normally occur. Paclitaxel is currently used in the treatment of ovarian, breast and non-small cell lung cancers.
They sell yew seeds on ebay. I will be buying some, and plant them then eat the berries/bark/the whole tree once it grows. Plants are good for a lot of diseases not just cancer.
Taxol® (1, paclitaxel), a poly-oxygenated naturally occurring diterpenoid isolated from the bark of the Pacific yew tree (Taxus brevifolia), is currently considered one of the most important drugs in cancer chemotherapy.1–4 Since its initial isolation in 1966 and subsequent structural determination in 1971, a tremendous amount of research focusing on the science and applications of paclitaxel has been performed.
https://patents.google.com/patent/US20060014968A1/en?q=paclitaxel&q=yew&oq=paclitaxel+yew
Paclitaxel is an anticancer compound primarily derived from the bark of the Taxus brevifolia (Pacific yew) tree. In the 1960's, the National Cancer Institute began a study of plant extracts exhibiting anti-cancer or anti-neoplastic activities. The crude extract of bark from the Taxus brevifolia was found to inhibit a variety of tumors. In 1971, paclitaxel was isolated and described by M. C. Wani et al. (J. Am. Chem. Soc. 93, 2325, (1971)), who defined the structure of paclitaxel using chemical methods and X-ray crystallographic analysis. In 1979, Schiff and coworkers demonstrated paclitaxel's novel mechanism of action. This mechanism includes binding to microtubules and preventing their depolymerization under conditions where depolymerization would normally occur. Paclitaxel is currently used in the treatment of ovarian, breast and non-small cell lung cancers.
They sell yew seeds on ebay. I will be buying some, and plant them then eat the berries/bark/the whole tree once it grows. Plants are good for a lot of diseases not just cancer.