SWAlexander
Senior Member
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So much pain and suffering—for what, if COVID-19 vaccine doesn't truly protect us?
Why protective antibodies fade after COVID-19 vaccines
https://www.nih.gov/news-events/nih...ctive-antibodies-fade-after-covid-19-vaccines
Original paper (subscription)
https://www.thehindu.com/sci-tech/s...-protection-wanes-quickly/article68810068.ece
THE GIST The challenges developers face are vaccines durability, lack of immune correlates of protection, and inability to protect against infection and transmission. But the greatest challenge is the inability to confer long lasting protection ▼ Long-lasting plasma cells migrate to the bone marrow and survive for an extended duration, promoting the production of antibodies. The goal of all vaccine developers is for vaccines to generate these calls in the marrow The future of vaccines protecting against challenging or emerging infectious diseases lies in the design of new immunogens, their release mechanism, and the mechanisms of action of various adjuvants
Why protective antibodies fade after COVID-19 vaccines
https://www.nih.gov/news-events/nih...ctive-antibodies-fade-after-covid-19-vaccines
Original paper (subscription)
https://www.thehindu.com/sci-tech/s...-protection-wanes-quickly/article68810068.ece
THE GIST The challenges developers face are vaccines durability, lack of immune correlates of protection, and inability to protect against infection and transmission. But the greatest challenge is the inability to confer long lasting protection ▼ Long-lasting plasma cells migrate to the bone marrow and survive for an extended duration, promoting the production of antibodies. The goal of all vaccine developers is for vaccines to generate these calls in the marrow The future of vaccines protecting against challenging or emerging infectious diseases lies in the design of new immunogens, their release mechanism, and the mechanisms of action of various adjuvants