Which form of niacinimide?

[maryb]

I'm low in B3 and doc said to take niacinamide. I called into the pharmacy this afternoon and was faced with 4 different forms - all Solgar.....WtH
Can someone direct me to the best one - also seem to remember a non flushing one??

I don't seem to be able to tolerate the bcomplexes so maybe I'll just have to try them one at a time, oh hell....

 

[Sea]

I know very little about this mary, I'm sure others who know more will chime in. I'm pretty sure though that the flushing happens with Niacin but not with Niacinamide

 

[Ema]

The flushing is from nicotinic acid which is part of what is typically called niacin.

Niacinamide is the other part contained in niacin and it doesn't cause flushing.

I had a hard time with flushing because the vasodilation increased my pain levels especially in my head. I'm tolerating niacinamide at 1000 mg twice daily just fine though. At that dose, it is thought to have antibacterial effects as well.

FWIW, I am taking the Thorne version of niacinamide.

Ema

 

[Sushi]

The flushing is from nicotinic acid which is part of what is typically called niacin.

Niacinamide is the other part contained in niacin and it doesn't cause flushing.

I had a hard time with flushing because the vasodilation increased my pain levels especially in my head. I'm tolerating niacinamide at 1000 mg twice daily just fine though. At that dose, it is thought to have antibacterial effects as well.

FWIW, I am taking the Thorne version of niacinamide.

Ema

Any reported dangers with a high dose of niacinamide? I've only been taking 500 mg per day.

Sushi

 

[Ema]

Any reported dangers with a high dose of niacinamide? I've only been taking 500 mg per day.

Sushi

Wikipedia, the grail of all knowledge, says doses up to 3g a day are not associated with liver toxicity.

 

[maryb]

thanks people @Ema I've ordered the Thorne one from iherb, - ridiculous that its cheaper than buying it the UK - now wonder they call it 'rip off Britain'
I'm so glad I didn't buy the niacin yesterday - I get so confused when confronted with someone who is obviously knowledgeable but not really telling me what I want!!!

 

[undcvr]

Any reported dangers with a high dose of niacinamide? I've only been taking 500 mg per day.

Sushi

I've read doses at up to 1-2 gm a day for alzheimer's but doesn't niacinamide quech methylation ? And you should not be taking it with methlyB12 ? I was told NADH is the best most active form of B3. It does work but it is also very expensive.

 

[Ema]

I've read doses at up to 1-2 gm a day for alzheimer's but doesn't niacinamide quech methylation ? And you should not be taking it with methlyB12 ? I was told NADH is the best most active form of B3. It does work but it is also very expensive.

I don't think it quenches methylation so much as soaks up excessive methyl groups. So if you are an overmethylator, it is beneficial in that respect. I'm not sure that it does anything if undermethylation is the problem.

I've wondered about taking it apart from mB12. I currently take mB12 about an hour before the AM dose of niacinamide.

I didn't have any luck with NADH. I don't think it can survive the digestive tract. I don't believe it is well absorbed sublingually as well. And it doesn't have the antibiotic benefits of niacinamide.

Ema

 

[Kimsie]

The orthomolecular doctors have been using niacinamide in doses up to 6 grams a day for about 60 years without anyone having liver damage. The people who have had actual liver damage were taking time release niacin, not niacinamide.