Where you taking NSAIDs at onset of disease? Connective Tissue ? CCI

[sb4]

I am curious at how many people where taking NSAIDs at the start of there illness. If the cause is CCI in some people, and if most people get ill after viral infection, then something must be causing degradation of the connective tissue in the neck.

NSAIDs are common to take when ill but they also cause connect tissue problems "Some of the effects of NSAIDs on the articular cartilage in OA include inhibition of chondrocyte proliferation, synthesis of cellular matrix components, glycosaminoglycan synthesis, collagen synthesis and proteoglycan synthesis. The net effect of all or some of the above is an acceleration of articular cartilage breakdown. "

 

[Rufous McKinney]

probably only aspirin.

 

[mattie]

Never took NSAID's. Ever.

 

[Gingergrrl]

I'm not voting @sb4 (b/c I don't want to screw up your poll results!) but the very first trigger of my illness (ground zero) was a neurotoxic reaction to Levaquin (Fluoroquinolone antibiotic) and I was taking Advil (an NSAID) at the same time which I later learned can make the reaction even worse.

Levaquin damaged my right triceps tendon/arm and I suspect taking Advil at the same time may have compounded the reaction. I'd love to know how many people with connective tissue issues were taking a Fluoroquinolone when they got sick? Approx 1.5 years after the Levaquin injury, I significantly improved only to get severe Mono/EBV about six months after that .

 

[Thinktank]

Nope, only paracetamol.
I suspect an even amount of people have taken a fluoroquinolone antibiotic which is 10000x more damaging to connective tissue than any NSAID. My neck pain started with the use of ciprofloxacin.

 

[Thinktank]

I'd love to know how many people with connective tissue issues were taking a Fluoroquinolone when they got sick?

I'd like to know that too. Perhaps we can start a new poll on that subject.

 

[sunshine44]

yes I was, a lot too for migraines from an anxiety med. Then the digestive issues began and the rest.

 

[Pisgah]

No NSAIDs here.

 

[perchance dreamer]

@sb4, my doctor of physical medicine has long maintained that NSAIDs cause connective tissue breakdown if taken long term. I finally broke the habit of taking 3 Advil at night and am so glad I did.

 

[perchance dreamer]

I was taking Advil because it was the only pain reliever that didn't constipate me or affect my mental functioning. I don't understand why more effort is not put into non- or at least low side-effect pain relievers.

CBD oil and the Meriva form of curcumin help me in oral forms, and Arnicare Gel is a great help as a topical. A nice thing about Arnicare is that it's non stinky.

 

[Gingergrrl]

I suspect an even amount of people have taken a fluoroquinolone antibiotic which is 10000x more damaging to connective tissue than any NSAID. My neck pain started with the use of ciprofloxacin.

I didn't realize that your actual neck pain started from Cipro. In my case, I had severe whiplash from a car accident in 2006 and then the Levaquin damaged my triceps/ arm in 2010. Because I could not use my right arm to grip things, my right shoulder and right side of my neck had to compensate which led to severe pain.

Every doctor, chiropractor, PT, etc, who examined my arm after the Levaquin injury said that the muscle/tendon felt more rough and fibrous (almost like a rubber band being stretched) vs. smooth.

I'd like to know that too. Perhaps we can start a new poll on that subject.

Maybe you and I could start a poll (so we don't take Sb4's thread off track re: NSAIDS). Would the poll specifically be re: FQ antibiotics and neck issues (or connective tissue issues in general)?

 

[Moof]

No for me too – other than aspirin (which I couldn't take because it aggravated my asthma), they weren't very common in the 1970s.

 

[robson]

No NSAIDs.
But I had taken 4x250mg of Tetracycline (antibiotic) every single day for eight straight years when I caught Mononucleosis in 2001. ME diagnosis finally in 2007.

 

[andyguitar]

It's a good subject for a thread @sb4 In my life time the availability of these drugs has become more widespread. To begin with they were only available on prescription, then you could get them without one but only from a Pharmacy. Today they are in almost every small shop and supermarket. Although they are sometimes needed they are not as safe as many would suppose.

 

[sb4]

It's a good subject for a thread @sb4 In my life time the availability of these drugs has become more widespread. To begin with they were only available on prescription, then you could get them without one but only from a Pharmacy. Today they are in almost every small shop and supermarket. Although they are sometimes needed they are not as safe as many would suppose.

Yeah that's why I got a stomach ulcer on onset of this disease. I had real bad tonsillitis so was taking doctor prescribed medicine (NSAIDs) and over the counter NSAIDs both at max dose and on an empty stomach. I was too stupid to realize that they where essentially the same thing.

 

[Gingergrrl]

Yeah that's why I got a stomach ulcer on onset of this disease. I had real bad tonsillitis so was taking doctor prescribed medicine (NSAIDs) and over the counter NSAIDs both at max dose and on an empty stomach. I was too stupid to realize that they where essentially the same thing.

I almost got an ulcer from NSAIDS in the early 90's when I was studying abroad and having severe period cramps (sorry for TMI) and did not have the proper pain meds. I initially did not know what was wrong with my stomach and did not associate it with the NSAIDS but figured it out in time before I got an actual ulcer. Now I am allergic to NSAIDS so it doesn't even matter! (And I was always allergic to aspirin life-long).

 

[Thinktank]

I didn't realize that your actual neck pain started from Cipro. In my case, I had severe whiplash from a car accident in 2006 and then the Levaquin damaged my triceps/ arm in 2010. Because I could not use my right arm to grip things, my right shoulder and right side of my neck had to compensate which led to severe pain.

Every doctor, chiropractor, PT, etc, who examined my arm after the Levaquin injury said that the muscle/tendon felt more rough and fibrous (almost like a rubber band being stretched) vs. smooth.

Maybe you and I could start a poll (so we don't take Sb4's thread off track re: NSAIDS). Would the poll specifically be re: FQ antibiotics and neck issues (or connective tissue issues in general)?

Have you been diagnosed officially with fluoroquinolone induced tendon damage?

Yes, i'd love to know how many other patients/members have been damaged by fluoroquinolone antibiotics. I'm too brain fogged now to set up a well thought out poll so i'll shoot you message later.
I think it's better to set up a poll re connective issues in general.

 

[Gingergrrl]

Have you been diagnosed officially with fluoroquinolone induced tendon damage?

I was in 2010 (both Fluoroquinolone Toxicity Syndrome and FQ induced tendon damage to my right triceps tendon). I was almost part of one of the class action lawsuits but back in 2010 they were only for people who had an actual tendon rupture from Levaquin or Cipro which thank God, I did not have.

Yes, i'd love to know how many other patients/members have been damaged by fluoroquinolone antibiotics. I'm too brain fogged now to set up a well thought out poll so i'll shoot you message later. I think it's better to set up a poll re connective issues in general.

No worries and send me a PM any time and we'll figure out a poll. I am very curious of the people who have connective tissue issues, how many had an adverse reaction to an FQ antibiotic earlier in their life.

 

[tiredowl]

Not back in 2008... But I was on tetracycline then.
So no.. no NSAIDs other than during the flu or whatever. But my onset wasn't after having the flu.
rarely take NSAIDS. I tried taking some aspirin before and was allergic to it. I will never take it again- I'm scared of taking anything besides paracetamol for pain (which isn't exactly good for the liver...)

Do all the NSAIDs have a negative effect connective tissue btw? I think I remember a physician that reccommended Celecoxib (?) for some patients.