@godlovesatrier - actually I think it was 5-htp that I recommended, not SAM-e, though that might work too!
@purplelady - I take a handful of stuff to sleep, about an hour before bed:
400 mg magnesium glycinate
1000 mg. inositol
2000 mg. glycine or gelatin
400 mg niacin
200 mg l-theanine
3 mg fast dissolve melatonin
We're all different, and many would not do well with that dose of niacin, but it works for me. It does cause the niacin flush, but that's fine with me - it helps put me to sleep.
The glycine and gelatin, which is high in glycine, can be tricky because when I first tried gelatin several years ago at night for sleep (1 tablespoon), it caused a severe detox reaction. I then learned that glycine is important for Phase II liver detoxification. I then went to a very small dose, gradually increased it over 6 months, until I finally stopped reacting to it and now can take it with no detox reaction. And my detox reactions in general have basically stopped - it used to be a weekly occurrence.
So I was taking 2000 mg of glycine for several years, but recently started gelatin before bed - 2 teaspoons dissolved, and it seems to be more effective than the glycine.
All of this puts me to sleep for about 4 hours. Then in the middle of the night I take
300 mg. magnesium glycinate
200 mg niacin
1000 mg inositol
200 mg l-theanine
3 mg fast dissolve melatonin
And go back to sleep.
A few more things:
If your cortisol is high at night, I don't think any of this would touch that insomnia. So it might be good to get your cortisol levels checked. I think the Adrenal Stress Index Test is best - it's a saliva test which measures cortisol levels via 4 saliva samples taking during the day/evening. Most doctors only order a blood test which is done first thing in the morning which tells you nothing about your night time level. when my cortisol was found to be high at night, I was told to take Seriphos (phosphorylated serine, NOT phosphatidyl serine, not the same thing) and this worked amazingly well. I found it was best to take it in the morning (had to do with circadian rhythm). When taken at night it caused a weird awful insomnia for me, but in the morning it just calmed me down and helped with sleep hours later at night. I had to experiment, titrate up, to find out the dose I needed.
Unisom can be very helpful too - an old antihistamine - it's different than benadryl, and much more effective for me. but my body easily adjusts to it so it can lose its effectiveness in a few weeks. It's also very strong! I save it for when I absolutely have to get 8 hours, and taking 1/4 tablet in the middle of the night (along with everything else) always does the job.
And a couple of more things you might try:
This post talks about a pose when done daily, worked very well for me to help with sleep. After some weeks though it started to rev up my thyroid, causing insomnia. Some time I want to try it again, and this time try cutting my thyroid med, instead of stopping the pose.
Grounding has also been helpful for me. When the weather is warm enough, I aim to sit outside with my feet on cement (no grass where I live) for at least an hour - and it helps put me back to sleep quickly. But it's too cold to do that right now.
One final thing (I think!) -
Box or 4-sided breathing can be very calming and help switch you from sympathetic to parasympathetic CNS:
Box breathing: How to do it, benefits, and tips (medicalnewstoday.com) I've started doing this in the middle of the night too! As you may have guessed, middle of the night is my worst time for sleep.
Finally (and I think this really is my last suggestion!) -
humming believe it or not is very calming. It helps produce nitric oxide and can switch you from sympathetic to parasympathetic. I've been combining humming (Ommmm or just mmmmm) with the box breathing - (1) inhale, (2) hold breath; (3) exhale while humming; (4) hold breath again, all the while inhaling and exhaling through your nose, no mouth breathing! - see above link.