Very bad allergies

[godlovesatrier]

Hello,

This year has been terrible for my allergies. It's like I've switched a gene on or something it's the worst I've ever had them. Whenever pollen has been medium or high I've had a sore throat the entire time.

I've tried loratidine at 3 x normal dose. Famotidine whilst walking and breathing in pollen + other periods. Citrizine. Diphenhydramine. Allegra (weirdly very unpleasant reaction to this).

These didn't help.

I'm going to get cromlyn from my GP and try that.

I've also tried histaquel (super expensive but didn't do anything). Histaquel has quercitin and nettle in it etc.

In 2021 and 22 I remember them being bad but only for a few months not what feels like the whole year.

Considering nothing has worked I'm not even convinced it's mast cell related. I have asthma so wondering if I could be related to that.

I'm also allergic to birch tree cross pollination fruits and I became allergic to penicillin about five years ago which includes amoxicillin. I break out in a Scarlett fever type rash all over my body if I take clindamycin.

Feel like it might all be connected but not sure how. Thoughts welcome.

Thanks.

 

[hapl808]

Don't know, but my decline from moderate into more severe felt allergy related. Exposure to a dog in my case. After that, all my previous 'normal' allergies became absolutely unbearable, along with allergies to things that never bothered me.

Tried pretty much everything - cromolyn, quercetin, vitamin C, ketotifen, Pepcid, Allegra (also very unpleasant reaction for me - palpitations, etc), Benadryl (good, but rebound and not viable long term), Claritin, Zyrtec, and so forth. Trying clemastine at the moment.

My 'coping' mechanism is just living in a place with as few triggers as possible, air purifiers, and I wear a P100 when it gets bad. I recommend trying a good P100. If that helps your allergies, then it's environmental and respiratory. If that doesn't help, then the histamine could be diet related or something else.

Frustratingly for me, I think it was both diet related (acid reflux coughing), respiratory allergens, and a major autoimmune trigger (my muscles felt like they were tearing apart fiber by fiber during allergy responses).

So in short, no damn idea.

 

[Judee]

My Mom's allergies were always worse than mine. Somehow we figured out if she took a little b6 and zinc (just the drugstore kind) her nose cleared up for a while. Another thing that also helped was Custom Probiotics B. Infantis but it's mega expensive...even just their sample size.

Also if you can figure out food allergies and do avoidance with those, your pollen allegies might improve. I think mine did significantly.

 

[sunshine44]

Have you tried something like this?

https://shop.heartandsoil.co/produc...G1GjJQlhh-Hef0vPel2DNwtHEfCC9UuwaAgX4EALw_wcB

Or Cordyceps?

I’ve had myself on a histamine cytokine lowering plan past few years. Im doing multiple things but they above have certainly been assisting in ways I couldn’t imagine.

Since I became so severe and nothing was working, I’ve discovered for my situation I no longer want to suppress the allergy symptoms but actually treat the root cause. Keep in mind I became allergic to mist every antihistamine though so I HAD to get creative. For me, part of that has been addressing getting my liver in better shape.

It’s quite a process. Im still bedridden but I’ve come a long ways from when I only ate 7 foods for 3 years and even some of those were starting to make mouth lips and throat swell plus hives and other unpleasant things.

Wishing you better health

 

[linusbert]

Hello,

This year has been terrible for my allergies. It's like I've switched a gene on or something it's the worst I've ever had them. Whenever pollen has been medium or high I've had a sore throat the entire time.

I've tried loratidine at 3 x normal dose. Famotidine whilst walking and breathing in pollen + other periods. Citrizine. Diphenhydramine. Allegra (weirdly very unpleasant reaction to this).

These didn't help.

I'm going to get cromlyn from my GP and try that.

I've also tried histaquel (super expensive but didn't do anything). Histaquel has quercitin and nettle in it etc.

In 2021 and 22 I remember them being bad but only for a few months not what feels like the whole year.

Considering nothing has worked I'm not even convinced it's mast cell related. I have asthma so wondering if I could be related to that.

I'm also allergic to birch tree cross pollination fruits and I became allergic to penicillin about five years ago which includes amoxicillin. I break out in a Scarlett fever type rash all over my body if I take clindamycin.

Feel like it might all be connected but not sure how. Thoughts welcome.

Thanks.

you really need to check on those:

- vitamin D , it directly influences mast cell response and also how immune system is reacting to this. there is no control of your allergies without it. for this asthma allergy type situation you should have a blood level of like 50ng/ml+ the whole year. depending on your weight thats at least a dose of like 2000-5000iu vitamin D a day. keeping it in a high level will overtime make a reshaping of cell types in your lung tissue to less inflamatory, this can take month and years but only works if you keep your D in that high level.
(not directly necessary in histamine and allergy, but i also would take vitamin k2 mk4 with D to make use of the calcium)
-- also careful there are many types of d3 , most common used is based on lanolin and sheep wool, some may have a allergy to this. there is also a variant of it based on plants and fungi, check for the "vegan" D. and there is that natural D contained in cod liver oil, it usually is in 1:10 ratio to retinol , so you might need to supplement D anyways as retinol is too much probably.

- zink , very important in histamine metabolism and in D metabolism

- magnesium , important to activate D

- b6 , as is this vitamin
(but always get a multi vitamin with all vitamins in natural balances and also multi mineral to not shoot your self out of balance, which happens in us sick folks faster than normal people)

- as mentioned, the multi mineral, and it should include potassium and magnesium. those are required so those lung muscles can relax but also is calcium which mediates inflammation and histamine output, thats very important in combination with vitamin D.
asthma medication is known to have potassium deficiency as side effect.

- selen , also works in the immunse system axis

- retinol (vitamin A, not beta carotene) , as does this, its the counterpart of vitamin D , unmodified cod liver oil does have a lot of retinol as does liver.

- copper , also very important for histamine metabolism, but very careful

- Vitamin C , keeps the histamine low

- good proteins , important for building transporters, enzymes etc. also for immunesystem. a certain immunoglobulin is used to mark substances as not dangerous. so be sure to have good proteins and enough.

 

[godlovesatrier]

Thanks all. Will start a few of these things.

 

[godlovesatrier]

Stated the zinc copper and selenium

I've been on 1.6 to 3g NAC since 2021 and I fear that may have slowly stripped my body of those metals.

 

[wabi-sabi]

What was your experience with cromolyn?

 

[Mouse girl]

Sounds like you are from the UK. All i know is that the summer I went there, I almost couldn't breathe at all and literally sneezed so hard constantly when i was outside until i found some med that worked with the hard core stuff. It even gave me asthma which I never had before. This was all before i got sick. My allergies get worse when i'm doing worse. I haven't been able to really breathe out of both nostrils since I've been sick and I can do more than many on here but I'm very ill, of course. Nettie pot crap is the worst thing for me, makes me much much worse. I've noticed my allergies and sinus problems are so bad now that i live in a house without carpet and with those stupid modern double pain, vinyl windows. They say that older homes with leaky windows are much healthier over all especially for allergies and those who are chemically sensitive but that's obvious. And carpet helps keep the dust and pet hair from constantly flying around, it sticks to the carpet and makes the indoor air quality better. I take zertec everyday and the last year, hydroxizine but want to get off that med as it's not for long term use and i use an air cleaner at night. It's great for white noise too so i can get more sleep. Allergies are soooo complex and different for everyone, so very hard to say what might help someone. Good luck though! I hope it gets better. With all the rain and weird climate change weather, perhaps times are jsut worse allegy wise over there?

 

[linusbert]

Stated the zinc copper and selenium

I've been on 1.6 to 3g NAC since 2021 and I fear that may have slowly stripped my body of those metals.

there are dependencies, zink and b6 work tightly together as are other vitamins.
selenium acts with vitamin e.

And carpet helps keep the dust and pet hair from constantly flying around, it sticks to the carpet and makes the indoor air quality better.

yikes. i bet a carpet vendor told you that ^^.
its theoretical true that a carpet picks up dust and dirt and keeps it there, and it accumulates until it cannot hold anymore, like a dust filter.
but it also attracts moisture and in combination with the dirt you have aggregated in that carpet a whole new planet of life in your house begins to evolve.
generel i would have as less cloth as possible in your living and bedroom. anything which attracts and keeps moisture is bad.

i would get rid of any carpet. and get a roomba or roborock instead and let the robot clean the floor a few times a day.
the roborocks has a station with bags, so you can easily just throw the bag out. optimal for allergics. i got one of those.

if its for optics, maybe a sisal carpet is a alternative. but those need to be cleaned too.

also keep in mind that carpets are usually treated with chemicals to keep them somewhat hygenic and mold free.