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Universal vaccine may be effective against any variant of any virus
Study: Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells
Scientists at the University of California, Riverside (UCR) has recently developed a revolutionary RNA-based strategy for a universal vaccine capable of combating any virus strain effectively and safely – even in infants and the immunocompromised.
Traditionally, vaccines are designed to anticipate the most prevalent strains of viruses like influenza and COVID-19, which requires yearly updates and reformulations. However, this new RNA-based vaccine eliminates the need for multiple versions by targeting a common component of the viral genome across all strains.
Unlike traditional vaccines that often contain a dead or weakened virus to trigger an immune response, this novel vaccine utilizes a live, modified virus. The significant difference, however, is that it does not depend on the usual immune system response involving T-cells and “memory” B-cells.
Instead, the vaccine employs small, silencing RNA molecules, making it suitable for use in individuals with compromised or underdeveloped immune systems, such as babies or those with immunocompromising conditions.
Moreover, the vaccine’s potential delivery via a nasal spray could address common aversions to needles, offering a more palatable alternative for many.
Study: Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells