Have you checked your B vitamin, glutathione, and amino acid levels? And loomed into ehsts goung in in your micribiome? All can have dramatic effects on mood, including depression, anxiety, irritability, and ability to concentrate.
Vortioxetine inhibits the re-uptake of serotonin (5-HT) and is an antagonist at 5-HT3 and an agonist at 5-HT1A receptors. This multimodal activity appears to be associated with antidepressant and anxiolytic-like effects.