Has anyone tested the integrity or effectiveness of toll like receptors? It would make sense to test this since some of them deal with viruses, so defects in their structure would hinder them and probably cause imbalances on other immune components in addition to chronic viral infections. Some of them deal with bacteria.
http://primaryimmune.org/about-prim...specific-disease-types/innate-immune-defects/
http://primaryimmune.org/about-prim...specific-disease-types/innate-immune-defects/