Th1 vs Th2

[cman89]

I know the science behind it, but what is the best way to determine Th1 dominance vs Th2 dominance?

 

[energyoverload]

I always hear about this and I think it is a far too simplistic way to classify the immune system. The either or approach. There actually may be dysfunction in both wings. With impaired NKC cytotoxic response to some antigens, but potentially chronic low grade cytotoxic activation of some components in an autoimmune type fashion. Shifting to Th1 too rapidly often causes aggressive pro-inflammatory cytokine production and there doesn't seem to be sufficient evidence that inducing this shift relieves symptoms - many seem to get worse and potentially stay worse..

 

[ahmo]

Here's an article for you:

Am I TH1 or TH2? http://www.wellnessalternatives-stl.com/am-i-th1-or-th2-or-th17/

 

[Jonathan Edwards]

I know the science behind it, but what is the best way to determine Th1 dominance vs Th2 dominance?

I think it is nonsense. There are T cells that have Th1 cytokines turned on and others with TH2 cytkines turned on but the idea of a 'TH1 response' or a TH2 response' seems to me imaginary - what I call immunobabble. You will see it everywhere but I cannot actually think what it would mean.

 

[cman89]

I think it is nonsense. There are T cells that have Th1 cytokines turned on and others with TH2 cytkines turned on but the idea of a 'TH1 response' or a TH2 response' seems to me imaginary - what I call immunobabble. You will see it everywhere but I cannot actually think what it would mean.

I think you do have a point Mr. Edwards

 

[gregh286]

I see redlabs have released a th1/th2 urine test.
http://www.redlabs.com/#!about1/c1h6u

Paper about it co-written by de meirleir downloadable from that page.
Well for €55 i gave it a go.
I scored a far right th2 as was expected according to the paper.
Whether its credible or even actionable...well its another story....

 

[Gingergrrl]

I thought Th1 dominant was when you constantly get sick with cold/flu or fever and feel ill/malaise, fever, sore throat, swollen lymph nodes (this is just an example) vs. Th2 is autoimmune such as Hashimoto's or Mast cells going crazy with allergic reactions but you don't feel ill/malaise and have zero fever, colds, flu etc.

Is this incorrect?

 

[Sushi]

I scored a far right th2 as was expected according to the paper.

So did I but in his office a few years ago it only cost 10 euros--but there were no lab fees really as they read it immediately in the office lab.

 

[South]

None of the expert sites can agree on what "supports" th1 vs th2, they can't even agree on what kind of pathogens are killed by which of these th's. Some of the scientific sites throw around words like "this one is humoral immunity" without describing further, and give lists of names of pathogens "killed" by one of the th's, lists which are then contradicted by the next scientific site I find.

Another site states "Bacterial and most viral infections increase your Th1 system" well, other people could say that maybe that means the body needs to increase Th1 to fight those infections, no explanation is ever given why we would want to instead take things to shift from Th1 to Th2.

I avoid sites that focus on this topic now.