Subcellular Structures on Neurons and Muscle Cells

Wishful

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https://www.sciencedaily.com/releases/2025/02/250207152716.htm

"Lorena Benedetti, a research scientist in the Lippincott-Schwartz Lab, was tracking molecules at high resolution along the surface of the ER in mammalian neurons when she saw that the molecules were tracing a repeating, ladder-like pattern along the entire length of the dendrites -- the branch-like extensions on brain cells that receive incoming signals.

Around the same time, Senior Group Leader Stephan Saalfeld alerted Lippincott-Schwartz to high-resolution 3D electron microscopy images of neurons in the fly brain where the ER was also forming regularly spaced, transversal structures."

This may not (or may) have anything to do with ME, but it's good to see this sort of discovery. If not this discovery, maybe a similar one will reveal the mechanism of ME.
 

sunshine44

The only way out, is through.
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https://www.sciencedaily.com/releases/2025/02/250207152716.htm

"Lorena Benedetti, a research scientist in the Lippincott-Schwartz Lab, was tracking molecules at high resolution along the surface of the ER in mammalian neurons when she saw that the molecules were tracing a repeating, ladder-like pattern along the entire length of the dendrites -- the branch-like extensions on brain cells that receive incoming signals.

Around the same time, Senior Group Leader Stephan Saalfeld alerted Lippincott-Schwartz to high-resolution 3D electron microscopy images of neurons in the fly brain where the ER was also forming regularly spaced, transversal structures."

This may not (or may) have anything to do with ME, but it's good to see this sort of discovery. If not this discovery, maybe a similar one will reveal the mechanism of ME.
Fascinating.

Thank you for sharing!
 

Murph

:)
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The ER membrane / calcium connection seems like the place a possible link to me/cfs could be found. Talking about memory is relevant: I don't know about you guys but I have the information storage and retrieval ability of someone 40 years older.

But I agree the main point here is that we're still learning about the structures and functions of the cell and its organelles. Maybe one day they'll stumble on something and be like, hold on, this explains a LOT.
 
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