Startup presents drug candidate against chronic fatigue syndrome

SWAlexander

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Original title: „Start-up präsentiert Arzneistoffkandidat gegen chronisches Erschöpfungssyndrom“
Google Translation see attachment
 

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SWAlexander

Senior Member
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Prof. Wirth highlighted MTC002, currently the most expensive drug available on the market.

There is still uncertainty regarding the necessity of continued treatment with Spinraza, a drug used for spinal muscular atrophy (SMA), after a one-time administration of Zolgensma. (
)

Meanwhile, scientists have made significant progress in understanding the underlying causes of post-COVID-19 muscle weakness, an issue that has affected a diverse group of patients.

Although many have long suspected the role of mineral and hormone imbalances in various forms of muscle weakness, doctors have so far been reluctant to conduct the necessary tests that could guide treatment options.

Several key diagnostic tests that could offer insights into muscle dysfunction include:

  • Serum potassium (K+): Evaluates potassium levels to identify hypokalemia or hyperkalemia, both of which can impair muscle function.
  • Serum sodium (Na+): Assesses sodium balance, critical for muscle contraction and overall cell function.
  • Serum chloride (Cl−): Determines chloride levels, essential for maintaining proper muscle membrane potential.
  • Bicarbonate (HCO3−): Helps detect acid-base imbalances, such as metabolic acidosis, which can affect ion transport.
  • VLCFA test: Measures very long-chain fatty acids to diagnose peroxisomal disorders that impact muscle energy metabolism.
I wonder how much longer it will take to get definitive answers.
 
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SlamDancin

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@SWAlexander One question, what about Serum Ca+? Mine has always been right at the upper limit and sometimes above. My serum levels of Na+, K+ and Cl+ have always been in normal range
 

SWAlexander

Senior Member
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2,132
Serum Ca+? Mine has always been right at the upper limit
Calcium (Ca) levels are often over-emphasized in test results. Elevated or low calcium levels can sometimes be attributed to hereditary factors, such as having fewer receptors, which affects calcium regulation in the body. However, other tests may provide more critical insights into your overall health and should not be overlooked.

If you're up for it, I'd recommend reading more on related tests and their significance, as they might offer a more comprehensive view of what's going on: https://swaresearch.blogspot.com/2024/10/diagnostic-tests-for-muscle-fatigue.html
 
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