Prof. Wirth highlighted MTC002, currently the most expensive drug available on the market.
There is still uncertainty regarding the necessity of continued treatment with Spinraza, a drug used for spinal muscular atrophy (SMA), after a one-time administration of Zolgensma. (
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Meanwhile, scientists have made significant progress in understanding the underlying causes of post-COVID-19 muscle weakness, an issue that has affected a diverse group of patients.
Although many have long suspected the role of mineral and hormone imbalances in various forms of muscle weakness, doctors have so far been reluctant to conduct the necessary tests that could guide treatment options.
Several key diagnostic tests that could offer insights into muscle dysfunction include:
- Serum potassium (K+): Evaluates potassium levels to identify hypokalemia or hyperkalemia, both of which can impair muscle function.
- Serum sodium (Na+): Assesses sodium balance, critical for muscle contraction and overall cell function.
- Serum chloride (Cl−): Determines chloride levels, essential for maintaining proper muscle membrane potential.
- Bicarbonate (HCO3−): Helps detect acid-base imbalances, such as metabolic acidosis, which can affect ion transport.
- VLCFA test: Measures very long-chain fatty acids to diagnose peroxisomal disorders that impact muscle energy metabolism.
I wonder how much longer it will take to get definitive answers.