Hi endomeister,
Thanks for your chart :Sign Good Job: . It's very interesting. I had my doubts about garlic...whether I was allergic to it, or sensitive to it??? Interesting as it's part of the Lillium family and I am allergic to Lilly flowers!!!
I notice it's on your chart as a potent stimulator of TNF-alpha and therefore inflammatory
Too bad it is in the Neuro Health Formula I have!!! Do you have some references I could read about it?
Thanks,
meryl :victory: PS I take Chlorella (Swisse), helps detox
I have seen conflicting information in regard to garlic. Here is a quote from an article: "Garlic derivatives have both a
stimulatory (7) and inhibitory (79) effect on lymphocyte proliferation and LPS-induced
TNF-alpha generation".
Remember that with autoimmune and autoinflammatory conditions (like CFS, Behcet's Disease, etc), patients often greatly overproduce tnf-alpha and other inflammatory compounds in response to any stimulation. So, if a food has immunomodulatory effects which are both suppressive and stimulative, the stimulative effects may dominate.
Here is a pubmed link with some information on alliin, a compound in garlic:
http://www.ncbi.nlm.nih.gov/pubmed/10501628
Remember, also, that stimulating tnf will lower glutathione levels as inflammation generates all kinds of toxins that glutathione must mop up.
Garlic is also said to be rich in citrulline, a precursor for arginine. Arginine stimulates NO which is already in overdrive in some inflammatory conditions. In addition, a cause/trigger of some auto-inflammatory conditions are the herpes family viruses like HSV1/2, VZV, etc. These viruses are stimulated by arginine. This is yet another mechanism through which garlic may produce inflammation.
To counter arginine, many of us take lysine (which in fact does help counter arginine and reduce inflammation).
The upshot is be careful with garlic if you have any autoinflammatory or autoimmune condition, or sense it is causing problems for you.