Severe consitpation, making ME worse?

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i was wondering if anyone has or had very severe constipation and if it made your ME worse? Mine is constant (can go a month without going to the toilet despite medication) and do wonder if it makes other symptoms worse. I know it was pressing on my organs in the past (showed up as doing so on scans) so caused things like shortness of breath but I've been wondering recently if it contributes to other symptoms or if it's one of those things you just adjust to and get on with (like pain)
 

Crux

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a million +1 thing can cause constipation. named by the sort of diagnose done.

nerves paralysis, high serotonine, low serotonine, missing microbes, wrong microbes, helminths ... blah blah blah

of course its bad as toxins cumulate in the blood, tissue...

by 30something a colleague told me he had two bowel movements a day.
i thought he is completely sick.
 
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