Ran my 23andme through GeneticGenie and need some help

[WD40]

I got my methylation profile and detox profile from GG and I'd like some help interpreting them please.

In particular I'd like some insight into the "NAT2 K268R" which I'm +/+ for, and the four +/+ I have on my methylation profile.

Are there any supplements that I should be taking, given my specific SNPs?

Am I a good or bad detoxifier of mercury?

Here are my results:

 

[WD40]

I've been watching a presentation by Benjamin Lynch on methylation and MTHFR defects and I'm learning a lot.

From what I have gathered so far, my homozygous mutations of COMT V158M, COMT H62H, and MAO A R297R all slow the breakdown of serotonin and dopamine.
I lose my temper easily and sometimes get quite angry at little stuff that shouldn't get me mad. I'm thinking there might be a connection.

I have been supplementing with a fair amount of N-Acetyl L-Tyrosine daily, thinking that it will help my sluggish thyroid. Is this a bad idea, given those SNPs?

What about Dimethylglycine?