Quad Muscle weakness/burning/pain

[Chardo]

Click here for video
This is a video of my quad muscle with barely any load. My quad muscles really bother me and feel like they are worsening. I can’t get around a lot but it seems my legs are starting to feel like they are losing function. It feels like I might fall one day. I am trying to decide if it’s worth going back to the neurologist. Previously nerve/muscle testing was normal (a couple years ago). It’s a huge energy investment for me to leave the house and I will definitely crash. But I’m not sure if this is just a worsening of my ME and Fibro. I haven’t been able to determine if this is something generally common in ME and it’s just part of the disease. I’m having a hard time deciding what to do. I wish it was easier to go in to the doctor but it’s such a horrible ordeal and I can’t really accomplish this one with virtual. Does anyone have this presentation of quad muscle weakness/burning? My other muscles do not feel this way… just the quads. Like there’s no energy in them, tight, locked, burning. It’s definitely worse in a crash but I gave it all the time. Any input is greatly appreciated.

 

[Pyrrhus]

Interesting, those look like the largest fasciculations I have ever seen.

My fasciculations are smaller and generally do not involve an entire muscle, just specific parts of a muscle.

Hope this helps.

 

[Pyrrhus]

Related discussion:

Muscle twitching (Fasciculations) and Limb jerking (Myoclonus) in ME
https://forums.phoenixrising.me/thr...tions-and-limb-jerking-myoclonus-in-me.84872/

 

[Chardo]

Are your fasciculations when loaded or only at rest?

 

[Pyrrhus]

Are your fasciculations when loaded or only at rest?

Both, in fact.

 

[Zebra]

I am trying to decide if it’s worth going back to the neurologist. Previously nerve/muscle testing was normal (a couple years ago). It’s a huge energy investment for me to leave the house and I will definitely crash.

I would encourage you to return to the neurologist and show him or her this video.

Your neuro might want to repeat a NCS/EMG on your lower limbs and/or bump you up to a neuromuscular specialist.

I realize the effort will result in a crash (this happens to me, too) but I think this is a significant symptom and worth investigating.

 

[Violeta]

@Chardo, do you have any other symptoms, such as dry mouth or difficulty with focusing vision?

 

[Chardo]

I have blurriness in my right eye frequently. No dry mouth though. I have plenty of saliva. But when I get stressed my mouth does feel chalky. I am frequently “wired and tired”, so I guess it happens quite a bit.

 

[Chardo]

I would encourage you to return to the neurologist and show him or her this video.

Your neuro might want to repeat a NCS/EMG on your lower limbs and/or bump you up to a neuromuscular specialist.

I realize the effort will result in a crash (this happens to me, too) but I think this is a significant symptom and worth investigating.

Yes that’s why I made the appointment. My legs are def one of my my most distressing symptoms. I hate going if it’s common in ME but it sounds like mine is maybe more extreme than what’s commonly seen?

 

[Chardo]

@Chardo, do you have any other symptoms, such as dry mouth or difficulty with focusing vision?

I have blurriness in my right eye frequently. No dry mouth though. I have plenty of saliva. But when I get stressed my mouth does feel chalky. I am frequently “wired and tired”, so I guess it happens quite a bit.

 

[Violeta]

I have blurriness in my right eye frequently. No dry mouth though. I have plenty of saliva. But when I get stressed my mouth does feel chalky. I am frequently “wired and tired”, so I guess it happens quite a bit.

"Wired and tired" can be related to riboflavin deficiency, but maybe other things, too, I wonder if you have any other signs of riboflavin deficiency to confirm it.

 

[Woof!]

Do you ingest sufficient Calcium and Magnesium? Low Ca++ and Mg++ cause all sorts of leg muscle pain, weakness, numbness and muscle fasciculations for me. Several doses of both are needed to stop it all Three doses of each is needed to prevent recurrence, as I know all too well because I get forgetful about taking all my doses at times - ugh!

I also have FM, BTW.

 

[Chardo]

"Wired and tired" can be related to riboflavin deficiency, but maybe other things, too, I wonder if you have any other signs of riboflavin deficiency to confirm it.

I will look into that but I haven’t had any abnormal vitamin labs. I do supplement with a few vitamins and it’s never really helped.

 

[Chardo]

Do you ingest sufficient Calcium and Magnesium? Low Ca++ and Mg++ cause all sorts of leg muscle pain, weakness, numbness and muscle fasciculations for me. Several doses of both are needed to stop it all Three doses of each is needed to prevent recurrence, as I know all too well because I get forgetful about taking all my doses at times - ugh!

I also have FM, BTW.

I do take both. I going to try some transdermal mag. Hoping it helps a little more.

 

[Woof!]

I do take both. I going to try some transdermal mag. Hoping it helps a little more.

I'm thinking I have an inherited issue with Ca++ being picked up at a cellular level, to the point where I have an appointment with a Ca++ specialist in March. I find that taking smaller doses of Ca++ citrate (400 mg) with Mg++ three times a day helps my muscles more than larger doses (600 mg) with Mg++ twice a day.

 

[Violeta]

I am seeing in searches that peroxynitrite is prevalent in fasciculations. I am not saying that is always the cause, but maybe someone will find that interesting.

I also see that peroxynitrite has an effect on calcium channels but I can only find it with respect to cerebral artery smooth muscle, myocardial contraction, and peroxynitrite is increased in exhaled breath condensate of COPD patients.