sb4
Senior Member
- Messages
- 1,678
- Location
- United Kingdom
Just wandering if some of us have pyruvate carboxylase deficiency as oppose to pyruvate dehydrogenase? I say this because:
I have trouble handling carbs yet also have lots of trouble with ketosis. Perhaps my struggles with ketosis could be due to low protein and faulty carboxylase = what little sugar I'm making isn't turning to oxaloacetate and I don't have enouth amino acids for anaplerosis;
I have a test result indicating problems with pyruvate and lactic acid;
I have low B6 which would be used for anaplerosis to bypass pyruvate carboxylase;
A recent visit to an osteopath said I had something wrong with carboybiotin but he didn't know what/why;
There doesn't seem to be a whole lot out there with regards to ideas on how to test / treat this. Not sure if high dose biotin would help (although it has helped some @BiotinJunkie ). I know high protein should work but this is no good for gastroparesis. Ideally I could find something like DCA to try and see if it increases my carb tolerance. Any idea's anyone? @nanonug
I have trouble handling carbs yet also have lots of trouble with ketosis. Perhaps my struggles with ketosis could be due to low protein and faulty carboxylase = what little sugar I'm making isn't turning to oxaloacetate and I don't have enouth amino acids for anaplerosis;
I have a test result indicating problems with pyruvate and lactic acid;
I have low B6 which would be used for anaplerosis to bypass pyruvate carboxylase;
A recent visit to an osteopath said I had something wrong with carboybiotin but he didn't know what/why;
There doesn't seem to be a whole lot out there with regards to ideas on how to test / treat this. Not sure if high dose biotin would help (although it has helped some @BiotinJunkie ). I know high protein should work but this is no good for gastroparesis. Ideally I could find something like DCA to try and see if it increases my carb tolerance. Any idea's anyone? @nanonug