Dr. Hertoghe, who is basically the authority on endrocrinology started growth hormone at a physiological replacement dose and was able to lower his dose as apparently it restored his normal pituitary GH output. If this is the case, I doubt you need to worry about pulsing it. Bodybuilding often do 5 days on 2 days off though. But they are using ridiculously huge doses. If you are just doing an IU or 2 I doubt it will even interfere with whatever little natural output you have. If you have a prescription for it I am assuming you are deficient in it anyway...