Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition:

[Violeta]

This seems to be helping.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6412213/


Schisandra chinensis is a plant whose fruits have a long-standing use in traditional Chinese medicine. They have been used in the treatment of diseases of the gastrointestinal (GI) tract, respiratory failure, cardiovascular diseases, body fatigue and weakness, excessive sweating, and insomnia [3].

They were also reported to reduce hunger, delay aging, increase vitality, and improve mental health [4].

They demonstrate neuro and hepato-protective, anti-inflammatory, antioxidative, detoxification, immunostimulant, antiviral, and anti-cancer activities, as well as cardiovascular and skin-protective properties [5,6,7,8].

Reviews of the pro-health effects of SCE focus primarily on their influence on the central nervous, sympathetic, cardiovascular, endocrine, and respiratory systems, as well as its adaptogenic, hepatoprotective, immunostimulant, antioxidant, ergogenic, and anti-stress activities [3,4,9,10,11].

This review provides updated information on the phytochemical composition of SCE and the mechanisms underlying its beneficial activity in humans, including its anti-cancer, antimicrobial, anti-diabetic, anti-obesity, and anti-aging actions.

 

[Violeta]

Effect of Schisandra chinensis Extract Supplementation on Quadriceps Muscle Strength and Fatigue in Adult Women: A Randomized, Double-Blind, Placebo-Controlled Trial​

https://pmc.ncbi.nlm.nih.gov/articles/PMC7177795/

Supplementation of SC extract may help to improve quadriceps muscle strength (QMS) as well as decrease lactate level at rest in adult women.

In the Schisandra group, the lactate level at rest was significantly decreased (p < 0.05), but had no change in the placebo group after 12 weeks.

 

[Violeta]

Effect of Saengmaeksan on Fatigue, Liver Function, and Immunity Combined with High-Intensity Training​

https://pmc.ncbi.nlm.nih.gov/articles/PMC10328733/

What do you think? Can we apply this information to ME/CFS?

In this study, they found the herbal combination of Lirio platyphlla, Panax ginseng, and Schisandra chinensis improves fatigue, liver function, and immunity in long-term high-intensity training. They used high-intensity training because long-term high-intensity training has a negative effect on these aspects.

We can't do high-intensity training, but elevated lactate and ammonia are common in ME/CFS.

The study:
We hypothesized that SMS intake will improve fatigue (ammonia, lactic acid), liver function (aspartate transaminidase (AST) and alanine aminotransferase (ALT)), and immunity (IgA, IgG, IgM) with high-intensity training.

These findings demonstrate that SMS intake can reduce ammonia, AST, ALT, and IgM levels, while causing an increase in IgA, which has a positive effect on fatigue reduction, liver function, and immunoglobulins in a high-intensity training or related environment.

PS: Lactate levels were not affected.

 

[andyguitar]

What do you think? Can we apply this information to ME/CFS?

Perhaps. Quick heads up here-rat study which shows that herb does have measurable effect.

 

[Violeta]

Perhaps. Quick heads up here-rat study which shows that herb does have measurable effect. View attachment 56016

Wow!

 

[Rufous McKinney]

Supplementation of SC

Schizandra fruit is one of the 37 herbs I consume in my custom chinese herbal formula. Thanks for posting this, as it's motivating me to consume some tea.