The lady serving me at the chemist yesterday was telling my that ibuprofen is not good long term for the liver or kidneys, but paracetamol is actually worse for the kidneys (not sure about liver). I prefer to use ibuprofen plus codeine, as the codeine helps my sinus-like head symptoms too, but that's obviously not ideal long term either.
My fiancé also takes it most days, as he was assaulted at work and got a bulged lumbar disk as a result. It's mostly ok now, but constant dull pain I think. Ibuprofen plus is now kind of regulated in Aus, we don't need a prescription but you can only buy it max once a week (most chemists give us a hard time or don't give it to us if we're getting it that often) and it requires you to show ID because it's on a national register. We usually have cold and flu tablets on hand, as they aren't regulated at all and provide some relief as the day tablets have codeine too.
The bad thing is that all pain relief medication is bad for your organs because they are hard to filter and excrete. So it is ideal to take them as little as possible. But at the end of the day, you have to live and be able to do stuff. So I figure try to find the medication that does the least damage with a decent benefit. Most medications have bad effects on the body in some way, it's a matter of weighing up the pros and cons. I also stick to the idea that the least amount of drug required is the best amount.
Oh and anything else you can do (lifestyle-wise, such as diet, drinking, environment, even using more natural cosmetics) to make life easier for your liver and reduce toxins is always a little plus. Our systems are sensitive and the harder we work our livers, the more of our limited energy is spent on eliminated toxins.