Nitric oxide and redox mechanisms in the immune response

[leokitten]

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100761/

Posting this paper if people haven't seen before to give background information on how NO and the immune system are related.

I put this here to go with the posts from @deleder2k on the endothelial dysfunction theory of Fluge and Mella and their recent patent applications for NO enhancers/donors and sGC activators.

 

[leokitten]

The section on viruses and NO is interesting, here's a part:

NO is also a critical component in the eradication of viruses. Viral replication is inhibited by the induction of iNOS and the subsequent production of NO (HIV-1, coxsackievirus, influenza A and B, rhino virus, CMV, vaccinia virus, ectromelia virus, human herpesvirus-1, and human parainfluenza virus type 3) [94]. Coxsackievirus and CMV murine models show that iNOS reduces viral burden and decreases latency.