• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

NIH STRIVE Consortium Immune Modulator Clinical Trial

Dakota15

Senior Member
Messages
320
Location
Midwest, USA
https://www.nih.gov/news-events/new...trategy-hospitalized-covid-19-patients-begins

9/22/23, NIH: "Clinical trial to test immune modulation strategy for hospitalized covid-19 patients begins"

"Part of NIH’s STRIVE Consortium (Strategies and Treatments for Respiratory Infections and Viral Emergencies), the therapeutic may prevent overactive immune systems from causing severe symptoms."

‘The drug being used to test the strategy of early intensification of immune modulation, abatacept (or Orencia), is manufactured by Bristol Myers Squibb, Princeton, New Jersey. Researchers think it may also be useful as an immune modulator for COVID-19 by tamping down over-active immune responses.’

"Abatacept works by binding to and blocking molecules that normally activate T cells, a key part of the immune system. Other immune cells may also be affected by the drug. For patients taking abatacept, the immune system may be less likely to “overreact” when fighting an infection such as COVID-19.."

'It is supported by the National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) in partnership with NIH’s National Center for Advancing Translational Sciences (NCATS).'