New approach to Epstein-Barr virus and resulting diseases May 23, 2024

[keepontruckin]

https://www.sciencedaily.com/releases/2024/05/240523153711.htm

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease.

 

[andyguitar]

Looks interesting @keepontruckin ,worth keeping an eye on this one.

 

[junkcrap50]

Researchers led by Professor Christoph Hess have deciphered how the immune cells infected with EBV -- the so-called B cells -- are reprogrammed. Known as "transformation," this process is necessary for the infection to become chronic and cause subsequent diseases such as cancer. Specifically, the team discovered that the virus triggers the infected cell to ramp up the production of an enzyme known as IDO1. This ultimately leads to greater energy production by the power plants of infected cells: the mitochondria. In turn, this additional energy is needed for the increased metabolism and the rapid proliferation of B cells reprogrammed by EBV in this way.

Emphasis mine. IDO showing up again.