Acquired mitochondrial damage is a normal part of aging, but is accelerated in chronic fatigue syndrome and many other metabolic disorders. Chronic deficiencies and methylation factors as well as gut imbalances destroys the mitochondrial membranes and lead to the modern day diseases we see today. At this point, the fact is, we need mitochondrial support. The main focus is to prevent Apoptosis cell death and it's imperative that we start mitochondria supportive therapy at the on set of CFS/ME.
Radio note: Oral lipid replacement therapy may not be in high enough dosage for some members to absorb into their system and may need to look into IV lipid therapy.
PK / Protocol
http://pkprotocol.com/
Radio note: Oral lipid replacement therapy may not be in high enough dosage for some members to absorb into their system and may need to look into IV lipid therapy.
The PK Protocol aids in regeneration of the cell membrane
Background: The lipid soluble nature of toxicity has led us to seize the complexity of neurological presentations by addressing them from a cell membrane perspective. Examination of red cell lipids and identification of nuclear DNA adducts as chemicals, pesticides, microbials and metals in subjects with Motor Neuron Disease, Autism, Multiple Sclerosis, Post Stroke, Epilepsy, Alzheimer’s and Parkinson’s Disease over the past eleven years in 9000 analyses has revealed a characteristic accumulation of very long chain fatty acids (VLCFAs), which comprise lipid rafts, or ceramides, revealing cell membrane derangement. Membrane phospholipid abnormalities with elevation of VLCFAs may be indicative of exposure to fat soluble neurotoxins resulting in suppressed peroxisomal beta oxidation of VLCFAs. Disturbances in methylation due to toxic exposure may destabilize the membrane phospholipid structure and alter DNA expression due to deficits in the enzymes Methylene Tetrahydrofolate Reductase (MTHFR) and Methionine Synthase.
Objective: The use of oral and IV lipids may facilitate stabilization of phospholipids in cellular membranes thereby addressing cell membrane integrity. The addition of intravenous phenylbutrate addresses neuroinflammation by increasing the beta oxidation of VLCFAs.
Procedure: To clear the bioaccumulation of toxins and stabilize membrane function we have embarked on a clinical treatment plan for the past five years to address the accumulation of aberrant lipids and ceramides with oral and IV phenylbutyrate, bolus intravenous phosphatidylcholine as Essentiale, methylation factors (folinic acid, riboflavin, methylcobalamin, tetrahydrobiopterin), and sulfation support (IV Glutathione).
Results: We have noted significant and sustained clinical neurological improvement within the first few weeks after initiation of oral and intravenous treatment in our patient population of 300 subjects.
Conclusion: The administration of Phosphatidylcholine, Leucovorin/Folinic acid, Glutathione and Phenylbutyrate may offer a new therapeutic strategy for neurological disorders involving neurotoxic exposure.
So you might be thinking: how can one treatment regimen work on so many different diseases? While there are a few root causes of acquired disease --among them toxins, infections and trauma-- the final common pathways of disease are all due to cellular damage and dysfunction. This can happen at the cell membrane, the DNA, or the mitochondria (some of you may have to harken back to high school biology class). So, very briefly, what the PK Protocol does is remove the accumulated toxins in and on the cells and introduces back the raw materials to repair the membranes. That process allows function to be restored. This is a very simple, yet profoundly complicated process. So what organs are damaged enough to impair function gives you your diagnosis, the protocol helps repair all the cells of the body, which is why it's applicable to Age Management (some of our patients got to meet Ed Kane, Dr. Kane's husband, who is 85, sharp as a tack, and lectures to physicians in the seminars). See more at: http://www.pbimedicine.com/3/post/2...-treatment-the-pk-patricia-kane-protocol.html
PK / Protocol
http://pkprotocol.com/
Last edited: