Low oxalate diet noticeably improved my fatigue, brain fog and mental health after just 3 days! It's an easy-to-do diet with minimal restrictions

Hip

Senior Member
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18,114
I have been following an easy-to-do low oxalate diet for the last few weeks, and have noticed significant improvements in fatigue, brain fog and mental health that appeared after just 3 days. I read that for people following a low oxalate diet, it is common for benefits to manifest quickly like this.

Given how easy this diet is to follow (the way I do it imposes minimal restrictions on what you can eat), ME/CFS patients might like to experiment with this diet, to see if they benefit.



I'd read discussions on low oxalate diets on this forum in the past, but never really gave the idea much credence. However, I started to notice that the day after eating spinach (which is super high in oxalates), I would often have a strong anxiety attack that lasted all day. This delayed adverse reaction to spinach alerted me to a possible issue with oxalates, and so I decided to give a low oxalate diet a go.

Oxalates are natural toxins present in many plant-based foods (vegetables, fruits and nuts) but not present in meat, fish or dairy. Oxalates have toxic effects on the nervous system, and are toxic to mitochondria. Plant don't want to be eaten, so make toxic oxalates in part to defend themselves against herbivores and pests.

Low oxalate diets are actually a standard medical treatment for people susceptible to kidney stone formation, as dietary oxalates promote kidney stones. But this low oxalate diet is also reported to sometimes help those with arthritis joint pains, muscle pains, brain fog, insomnia, and digestive issues.

Most people consume around 200 to 300 mg of oxalate daily in their diet. A low oxalate diet aims for no more than 40 to 50 mg daily. I have not been so strict, and on my own low oxalate diet, I am probably eating around 80 mg daily. Because I am not that strict, following this diet involves very little changes to what I normally eat.

What I have done is simply avoid the foods that are particularly high in oxalates, such as the following (whose per portion oxalate content is given in brackets): spinach (547 mg), Heinz baked beans (96 mg), carrots (30 mg), oranges (23 mg), beetroot (38 mg) wheat bran (36 mg), dark chocolate (34 mg), peanut butter (19 mg), cashew nuts (64 mg), kiwi fruit (27 mg), and a few others.

Apart from avoiding these foods, I am still eating pretty much the same diet as I was before.

Although potatoes (26 mg) and wholemeal bread (14 mg per slice) are highish in oxalate, removing these from my diet would be more difficult, so I am still eating potatoes and wholemeal bread (I may switch to white bread, which only has 4 mg per slice). Though if you want to be stricter, in your meals you can swap potatoes for white rice, which is only 4 mg per portion.

My trick is to take a 400 mg calcium tablet with each meal. Calcium binds to the oxalates in the gut, and stops them being absorbed. A glass of milk will contain a similar amount of calcium. So by taking calcium with each meal, you can be less strict with your low oxalate diet.

And interestingly, I learnt that vitamin C may metabolise into oxalate in the body. One study says the breakdown of 60 mg of vitamin C could potentially result in the formation of 30 mg of oxalate in the body. So I now avoid high dose vitamin C supplements.



It's hard to get reliable information on the oxalate content of foods, because websites sometimes have contradictory information. But I read that the recently-updated Harvard list is considered the most reliable (in that weblink you can download the "Oxalate Table" as a spreadsheet).

Some food items are not in the Harvard list, so then I used this source and this source to obtain the oxalate content data.

I then compiled my own food list, based on some of the foods I usually eat, using the Harvard source where possible. Below is my list, giving the oxalate in a single portion of various foods, with the highest oxalate content foods at the top of the list.


Oxalate Content in a Single Portion of Various Foods
Rhubarb, ½ cup, 799 mg
Spinach, ½ cup, 547 mg
Swiss chard, ½ cup, 293 mg
Sweet potato, ½ cup, 158 mg
Heinz baked beans, ½ cup, 96 mg
Cashews, 28 grams (14 nuts), 64 mg
Hot chocolate, 2 heaped tsp, 41 mg
Beetroot, ¼ cup, 38 mg
Bran flakes, 1 cup, 36 mg
Dark chocolate, 20 grams, 34 mg
Carrots, ½ cup, 30 mg
Peanuts, 28 grams, 29 mg
Kiwi fruit, 27 mg
Potato salad, ½ cup, 26 mg
Mange tout, ½ cup, 26 mg
Dates, 5 dates, 26 mg
Aubergine (eggplant), ½ cup, 26 mg
Tinned tomatoes, ¼ cup, 25 mg
Blackberries, ½ cup, 23 mg
Orange, 23 mg
Chicory, 10 grams, 21 mg
Liquorice, 10 grams, 21 mg
Blueberries, ½ cup, 19 mg
Peanut butter, 1 tbsp 19 mg
Rice, brown, 1 cup, 19 mg
Bread, whole multigrain, 1 slice, 18 mg
Crisps, 25 grams, 17 mg
Brussel sprouts, ½ cup, 17 mg
Spaghetti, 1 cup, 16 mg
Tangerine, 16 mg
Leeks, 1 cup, 15 mg
Celery, ½ cup, 15 mg
Bread, whole wheat, 1 slice, 14 mg
Green beans, ½ cup, 13 mg
Tinned pineapple, ½ cup, 12 mg
Bell pepper, ½ cup, 11 mg
Banana, 10 mg
Olives, 6 olives, 10 mg
Avocado, 9 mg
Tomato, ½ cup, 8 mg
Red kidney beans, 50 grams, 8 mg
Cup of tea, 6 mg
Broccoli, ½ cup, 6 mg
Asparagus, ½ cup, 5 mg
Rice, white, 1 cup, 4 mg
Bread, white, 1 slice, 4 mg
Lima beans, 50 grams 4 mg
Watercress, 1 cup, 4 mg
Parsley raw, 1 tablespoon, 4 mg
Broccoli, ½ cup, 4 mg
Lettuce, 1 cup, 3 mg
Endive, 1 cup, 3 mg
Cup of coffee, 2 mg
Sweetcorn, ½ cup, 2 mg
Peas, ½ cup, 2 mg
Cauliflower, ½ cup, 2 mg
Pear, 2 mg
Apple, 1 mg
Strawberries, ½ cup, 1 mg
Grapes, ½ cup, 1 mg
Peach, 0.5 mg
Cabbage, ½ cup, 1 mg
Cucumber, ⅛ cup, 0.5 mg
Plum, 0.1 mg
 
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Wishful

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I wonder whether there are at least a few PWME that get worse if they don't get enough oxalates, since most ME treatments seem to have some in good and bad responses. I'm in the middle group: avoiding oxalates had no effect.
 

hapl808

Senior Member
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2,328
That's interesting. I may try that. I didn't realize carrots were high in oxalates - I tend to have cooked carrots frequently as I thought they were a pretty safe food.

I'd have to change quite a bit (dark chocolate, almond butter, rye bread), but I've done much more restrictive diets in the past - especially ones like Carnivore that you have to follow for months or people say you're doing it wrong.

I doubt it'll make a big difference. I did cut out spinach awhile ago just because it seems unusually high in a few things like oxalates. But I just don't eat that much food - maybe in a day I'll have one carrot, a small white potato, boiled chicken, dark chocolate, rye bread, almond butter. But you never know - I've certainly wondered about very small amounts of histamine, as that seems to affect me variably.
 

Hip

Senior Member
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18,114
I doubt it'll make a big difference. I did cut out spinach awhile ago just because it seems unusually high in a few things like oxalates.

I suspect taking a calcium tablet with each meal (to prevent oxalate absorption) may be the most important part of my oxalate protocol.

I've hardly made any changes to my regular diet, and have not drastically reduced my oxalate intake; thus my dietary changes may be less important than taking calcium, in terms of reducing the oxalate burden on the body.

So I think some ME/CFS patients might benefit just by taking calcium alone, with very minimal dietary changes required.



The only dietary changes I have made on a daily basis are: stopping dark chocolate (I would eat around half a bar of dark chocolate each day, which is around 50 grams), stopping my favourite toast with peanut butter snacks, stopping oranges and tangerines, and stopping bran flakes breakfast cereal. And of course being mindful of the very high oxalate foods like spinach and avoiding those.

That's hardly a great change in diet, yet I've had very noticeable improvements in brain fog, fatigue and certain mental health symptoms.

So I suspect that taking 400 of calcium with each meal, which binds to the oxalates and prevents their absorption in the gut, may be the most important aspect of my oxalate protocol.

If you have not got any calcium tablets handy, then as an alternative, drinking a large glass of milk (say 200 ml) with each meal will provide around 300 mg of calcium.

It would be interesting to see if just drinking a glass of milk each time you eat a meal ir have a snack might help some ME/CFS patients.

If this works for you, you can expect the benefits to manifest within two or three days, because there is usually a fast response to following a low oxalate diet.
 
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hapl808

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2,328
I suspect taking a calcium tablet with each meal (to prevent oxalate absorption) may be the most important part of my oxalate protocol.

Do you counterbalance with magnesium, take a combo, or just extra calcium?

The only dietary changes I have made on a daily basis are: stopping dark chocolate (I would eat around half a bar of dark chocolate each day, which is around 50 grams),

I'm about the same. I've stopped at other times, but usually restart as I find dark chocolate gives me a bit of a boost and improves bowel movements, too. That said, easy to stop for a bit so I'll probably try it once I finish my current carrots and other higher oxalate foods (don't really want to waste them, as I don't expect the diet to make a difference - but why not try).
 

Florida Guy

Senior Member
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259
@Hip a very excellent post. You clearly spent some time looking up that info and explaining the results. I like the idea of changing diet rather than trying a new drug with possible side effects

We just have to eat from the left side of the chart. Calcium may play a role as well. The question becomes how many will benefit and for how long?
 

Hip

Senior Member
Messages
18,114
Do you counterbalance with magnesium, take a combo, or just extra calcium?

I've just stared taking some magnesium as well, as calcium and magnesium should ideally be taken in a ratio of around 2:1. So I take a 500 mg magnesium tablet daily, which counterbalances the 2 x 400 mg of calcium I take daily with meals.
 

junkcrap50

Senior Member
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1,384
How do you know that the lists of oxalate quantities and low oxolate foods are accurate?

I found them to be somewhat contradictory when I tried a low oxalate diet. Didn't do much for me unfortunately.
 

helen1

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Location
Canada
I’ve been on a low oxalate diet for 9 months. I had no success trying to treat an overactive bladder, then read that oxalates can crystallize in the bladder too, not just in the kidneys and joints (and other areas). Bladder oversensitization is the main symptom of oxalates embedded in the bladder.

So I gave low oxalates a try and my bladder is slowly normalizing. For most people it takes weeks or months to see improvement. I’m getting up fewer times at night to go to the bathroom, that’s my measurement of progress!
 
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