Is there any significance to never feeling 'sick'?

outdamnspot

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Since I became severe 3 years ago, I've never felt 'sick' in the traditional sense, outside of one bout of bronchitis a few months ago. When my friend crashes or gets PM, it's accompanied by more pronounced flu-like symptoms.

All of my symptoms seem to be hormonal (i.e. 'severe adrenal fatigue', low thyroid etc.), neurological (balance problems etc.), and psychological (severe depression, cognitive impairments).
 
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I haven't been "sick" with cold/flu in about 7 years. I think it is because I have high lactic acid. Good for destroying other pathogens, but bad for fatigue and muscle soreness.
 

outdamnspot

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I haven't been "sick" with cold/flu in about 7 years. I think it is because I have high lactic acid. Good for destroying other pathogens, but bad for fatigue and muscle soreness.

I think I was referring to 'flu-like' symptoms or subjective inflammation as a component of one's CFS. I was reading back and found a post where @Gingergrrl said something like elevated TH1 is associated with viral-type symptoms, whereas TH2 might be associated with autoimmunity and not really feeling 'sick' (apologies if I have that wrong), though I wasn't sure if there was credence to the idea since I know there's some debate around TH1/TH2.
 

Seven7

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I never felt "sick" or fluish until year like 5 or so. I was gradual onset. Mostly I felt muscle pain and extreme fatigue at first (and sleep disturbances). Brain symptoms also.
 

Gingergrrl

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I was reading back and found a post where @Gingergrrl said something like elevated TH1 is associated with viral-type symptoms, whereas TH2 might be associated with autoimmunity and not really feeling 'sick' (apologies if I have that wrong), though I wasn't sure if there was credence to the idea since I know there's some debate around TH1/TH2.

I might have typed that a few years ago based on something I'd read or one of my doctors told me. I actually don't even remember typing it but have no doubt that I did! I vaguely remember someone telling me that TH1 was when your immune system was shifted toward the viral "feeling sick" side vs. TH2 was shifted toward the allergic reactions or autoimmune side. But truthfully, I have no idea if this is correct or if these terms (TH1 and TH2) are even still currently used vs. outdated?
 

outdamnspot

Senior Member
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924
I might have typed that a few years ago based on something I'd read or one of my doctors told me. I actually don't even remember typing it but have no doubt that I did! I vaguely remember someone telling me that TH1 was when your immune system was shifted toward the viral "feeling sick" side vs. TH2 was shifted toward the allergic reactions or autoimmune side. But truthfully, I have no idea if this is correct or if these terms (TH1 and TH2) are even still currently used vs. outdated?

I have no idea either. The site selfhacked seems to be a big fan of labeling stuff TH1 or TH2, but I've read on here it's not that simple and more of a false dichotomy. It piqued my interest because I keep wondering if my own condition is autoimmune, and I thought not 'feeling sick' could relate to that.
 

Gingergrrl

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It piqued my interest because I keep wondering if my own condition is autoimmune, and I thought not 'feeling sick' could relate to that.

It's certainly possible and I have not been "sick" in a traditional sense in 5.5 years (in January it will be six years). Have you had any autoimmune testing done? That would be much more accurate than the TH1/ TH2 stuff which I'm not sure is diagnostic of anything by itself.
 

outdamnspot

Senior Member
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It's certainly possible and I have not been "sick" in a traditional sense in 5.5 years (in January it will be six years). Have you had any autoimmune testing done? That would be much more accurate than the TH1/ TH2 stuff which I'm not sure is diagnostic of anything by itself.

I had ANA and ESR, both of which were negative. According to my doctor, that was enough evidence I don't have an AI disease *shrug*. They also said false negatives weren't possible.

I did have thyroid antibodies, albeit in range.
 
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Gingergrrl

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I had ANA and ESR, both of which were negative.

These are both kinda vague and unspecific tests and my ESR was always in the normal range. I have no idea if you have an autoimmune issue but I wouldn't rule it in or out just on those two tests (for anyone, not just you)!
 

outdamnspot

Senior Member
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924
These are both kinda vague and unspecific tests and my ESR was always in the normal range. I have no idea if you have an autoimmune issue but I wouldn't rule it in or out just on those two tests (for anyone, not just you)!

Outside of specified antibody testing, are there any other standard AI tests a GP could do?
 
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