The efficacy does make me wonder about phenibut, racetams, baclofen ans othergaba analogues Or agonists That May be safer
I have read about possible dependence with Phenibut.
Noofen is pharma-grade (medicine) whereas Phenibut is non pharma-grade (supplemente), but last the same products. It is availible as medicine in eastern europe and will usually not prescribed longer then 4weeks. Depending on the dosage it will support
"feelings off well beeing" and help against anxiety, social phobia, sleep disorders, insomnia and ticks (stuttering, Meniere's diseas and so on).
The medical dosages for treating asthenic and anxious-neurotic states are usually 250-500mg 3x times daily. High daily dosages are in the long term sometimes associated with hepatotoxicity (fatty liver) and dependency.
Most long term Phenibut users (e.g. not prescibed by a doctor) usually take it few days in a row and stop for few days and so on. Doing so may reduce the risc to build up any tolerance and side effects.
Balcofen is a muscle relexanxe and sometimes offlabel prescribed against Fibromyalgia muscle cramps and pain. (in my case it didnt help)
Piracetam is a GABA derivate without GABAergic effects, it is cholinergic and act at NMDA rececptors or whatever so. It has been assumed some neuroprotective properties and may obvisiously help few ppl. decreasing cognitive fatigue.
About Benzos and dependency:
Usually, short acting classes that fast kick´in (like Ativan/Lorazepam, Xanax) are associated with a significant higher risc for dependency. Slower floating and longer lasting classes like Clonazepam have a lower dependency risc. Several years ago the doctors put me 1year on Diazepam and later on Clonazepam. I never had any withdrawls from it, nevertheless I am carefully with Benzos and exspecialy any short acting stuff.
However, it may also depend from ppl. to ppl. how fast dependency + tolerance occur.
Many ppl. will get addicted very quickly whereas few folks can use such medicine for a long period off time without any problems. It is a difficult topic and hard to judge, because you dont know at last for sure if you have a fast predisposition for dependency or not.