High Dopamine / Methylation

[Hope78]

Hi!

In 2014 I was tested for neurotransmitters and was very high in dopamine, normal in norepinephrine, normal to high in serotonine and low in epinephrine.

I now repeated the test with nearly the same result: still too much dopa and low in epinephrine.

High dopa is probably due to slow versions of MAO A+B and COMT. Low epinephrine is about being short in methyl groups.

The dilemma: as soon as I try to boost my methylation (SAMe, TMG, methylB12 and so on) my dopamine rises and as it's already elevated I feel agitated with anxiety and very vidid nightmares. A big no because insomnia is one of my main problems.

So any suggestions how I can improve my methylation without further rising dopamine?

Are there any dopamine lowering supplements I am not aware of?

Thank you!

 

[JaimeS]

The dilemma: as soon as I try to boost my methylation (SAMe, TMG, methylB12 and so on) my dopamine rises and as it's already elevated I feel agitated with anxiety and very vidid nightmares. A big no because insomnia is one of my main problems.

SAMe would elevate serotonin, and that may well contribute to feelings of anxiety and crazy dreams. A lot of the high serotonin and high dopamine symptoms are similar.

If you are 'very high' in dopamine, you might want to talk to a physician you trust about dopamine-blockers.

If you don't have a physician you can trust, you might want to check out Bacopa monierii -- here is a list of research on its effect on dopamine and on serotonin.

I wouldn't aim for methylation right away... is there a reason that's the type of treatment you're going for?

-J