JillBohr
Senior Member
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- Columbus, OH
I know this is unrelated to ME/CFS but I can not help but wonder if glioblastoma brain tumour patients have XMRV. My grandfather died of prostate cancer in the mid 80s and my father died of a glioblastoma brain tumour in 1996. Two years later, my oldest son was born and he has autism. My father got sick in the spring of 1996. He thought he had the "flu" and could not get out of bed for several days. My sister-in-law went through this in 1996 as well but she ended up being diagnosed with ME/CFS almost two years later after going through a series of testing. My family was very healthy and very active and we have gone downhill since then. Anyway, there have been some articles published regarding how CMV is active in brain tumour patients. The Economist published a great one but it is no longer available on the internet regarding this particular brain cancer. Here is a link to another one:
http://open.salon.com/blog/amytuteurmd/2009/01/12/does_a_common_virus_cause_brain_cancer
"The saga began in the late 1990s, when Charles Cobbs, a neurosurgeon then at the University of California, San Francisco, started pondering the link between inflam*mation and brain cancer. Malignant tu*mors are often associated with abnormal immune activity, and he wanted to know why. Is it just something that happens out of the blue, or is it possible that theres something maybe driving that inflamma*tory cascade? he recalls wondering.
Because they elicit immune responses, in*fections immediately sprang to mind as pos*sible candidates. Cobbs and his colleagues analyzed glioblastoma samples from 22 pa*tients and found that all harbored CMV. Four out of five people have this virus, which remains in the body for life. Usually a per*sons immune system keeps CMV in a la*tent state in which it does not replicate, but Cobbs found the virus actively reproducing in these tumor cells and not in healthy cells nearby. It was stunningly obvious that these tumors were infected, says Cobbs, whose findings, published in Cancer Research in 2002, were confirmed in 2007 by Duke University neuro-oncologist Duane Mitchell."
I can not help but wonder if XMRV is reactivating common viruses not only in ME/CFS but other diseases as well.
http://open.salon.com/blog/amytuteurmd/2009/01/12/does_a_common_virus_cause_brain_cancer
"The saga began in the late 1990s, when Charles Cobbs, a neurosurgeon then at the University of California, San Francisco, started pondering the link between inflam*mation and brain cancer. Malignant tu*mors are often associated with abnormal immune activity, and he wanted to know why. Is it just something that happens out of the blue, or is it possible that theres something maybe driving that inflamma*tory cascade? he recalls wondering.
Because they elicit immune responses, in*fections immediately sprang to mind as pos*sible candidates. Cobbs and his colleagues analyzed glioblastoma samples from 22 pa*tients and found that all harbored CMV. Four out of five people have this virus, which remains in the body for life. Usually a per*sons immune system keeps CMV in a la*tent state in which it does not replicate, but Cobbs found the virus actively reproducing in these tumor cells and not in healthy cells nearby. It was stunningly obvious that these tumors were infected, says Cobbs, whose findings, published in Cancer Research in 2002, were confirmed in 2007 by Duke University neuro-oncologist Duane Mitchell."
I can not help but wonder if XMRV is reactivating common viruses not only in ME/CFS but other diseases as well.