Dr Chia finds enterovirus ME/CFS patients given the antiviral remdesivir for several days remain in remission for up to 9 months

Hip

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A new study by Dr John Chia finds that 75% of enterovirus ME/CFS patients who were given a 5 to 10 day course of the intravenous antiviral remdesivir obtained remission within 2 to 6 weeks of this treatment, and remained in remission for a period of time ranging from 6 weeks to 9 months.

This is impressive, since for some enterovirus ME/CFS patients, they might only need to take a course of remdesivir every few months in order to remain in remission.

Though it's not entirely clear from the study whether "remission" means complete cessation of all ME/CFS symptoms (which is the usual definition of remission), or whether by "remission" Dr Chia just means substantial improvement in symptoms.



In the body, remdesivir converts to GS-441524, and then this converts into the active compound GS-443902, which is antiviral for RNA viruses like enterovirus.

People whose cats develop the normally fatal viral disease of feline infectious peritonitis (FIP), which is caused by feline coronavirus, will sometimes obtain some GS-441524 to give to their cat. Usually it requires 12 weeks of daily injections of GS-441524 to save the cat. The total cost of treatment is around $5000. GS-441524 can also be given orally, but the oral bioavailability 57%, so a lot is wasted compared to injection. 1

A few years ago, GS-441524 for treating FIP could only be found on the black market, but nowadays it can be legally obtained from a vet.

GS-441524 would likely work just as well as remdesivir for treating enterovirus ME/CFS.
 
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cfs since 1998

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I've never heard of remissions that fast from any treatment (except from steroids and other "symptomatic" bandaid type treatments with temporary effects). This is unprecedented and sounds too good to be true but let's hope that it is.

If it works that quick, it should not be too difficult to do a double-blind placebo controlled trial. Let's hope Dr. Chia is able to put one together.

I've been hesitant to try Dr. Chia's favored treatment of oxymatrine becuase it's apparently bad for autoimmune diseases and I already think ME/CFS has a strong autoimmune component.
 
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cfs since 1998

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He also tested paxlovid. He reported that 75% improved on remdesivir and 50% on paxlovid. Seems high considering so/so results of paxlovid on Long COVID patients.
 
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