My integrative Internist (an MD) had my Boron level taken with a multitude of other tests and it showed I had no Boron (Boron - Non Detected - mcg/ml). This is despite a diet that should have allowed for such. I received a copy of the lab results in the mail before the appointment and he had previously given me an article on Boron. I read through it and ordered some 3mg caps, and took 3 of them for a total of 9 mg a day - with my 5000iu of Vitamin D3 and a host of other supplements. I had also read much about possible side effects of too much Boron so wanted to err on the side of caution and thought the 9 mg would be OK until I saw the doctor. When I saw him yesterday, one of my continued symptom complaints was cognitive clouding, poor cognition in general, memory problems. As I said to him, "I feel like someone just hit me upside the head with a baseball bat." He was going through my supplement list and mentioned the Boron. I reiterated the 9 mg and he said I should be taking 90 mg. That is right - 90 mg! He said the 9 mg would not help cognition, but the 90 mg would. I started thinking that would require 30, 3 mg caps - hmm - that is a lot!. Well he had Boron 30 mg as Potassium Borate, which he gave me. When I got home I looked to see if it was available on the Internet. I could find the lab that made it, but it was not for sale. Likely a good thing with a high dose and I see him again in about two weeks so it is all under doctor supervision. That being said, I popped three, for my total of 90 mg as I had had an morning appointment and it was still in the AM, as indicated for use. He had also boosted me up to 500 mg of Pregnenolone, but I only took an additional 100 mg with my Boron. Between the two, it felt like my brain had been hooked up to a jumper cable - actually a good feeling, and rather relaxing in some regard as it seemed to cut into the debilitating fatigue for a bit. It was not like "instant all is well" but more like "OK something is going on here and it is not bad." I had not slept much the night before and I ended up just closing my eyes, seeing some interesting visual patterns on the back of my eyelids and then going into a very deep, and much needed, sleep. Go figure. Am trying again this morning and will see how it goes. Just as an FYI - would not go trying any of this unless you have a medical doctor guiding you in that direction. 90 mg of Boron is a high dose, compared to what you may find on the Internet. So is 500 mg of Pregnenolone. Aside from other supplements, am also on a rather high dose of DHEA (100 mg). My DHEA-S level was in normal range, but my Pregnenolone was low on the blood tests. All this is complicated stuff. The doctor is well known in the field and affiliated with a local hospital, so I have a fair amount of trust in him. Hope this helps someone.