Distinguishing CFS - New Zealand Research

[Old Bones]

Press release from New Zealand providing more confirmation of two-day Cardiopulmonary Exercise Testing (CPET) abnormalities in those with ME/CFS:

http://www.scoop.co.nz/stories/GE1705/S00067/distinguishing-chronic-fatigue-syndrome.htm

"Dr Lynette Hodges from Massey University’s School of Sport and Exercise recently conducted a study comparing the physiological responses of CFS/ME, Multiple Sclerosis (MS) and healthy controls following a repeated maximal exercise test."

“On the second exercise test, those with MS and those who were healthy were able to repeat the same results on the exercise as on day one. However, those with CFS/ME were unable to achieve this and reached their anaerobic threshold faster and at a lower workload compared to day one,”

“Our study also showed that some individuals with CFS/ME took up to four weeks to recover following the two exercise tests, which was not apparent in the healthy individuals who were back to normal the following day.”

 

[Timaca]

Really nice that they are doing that kind of research...and are continuing to study it!

 

[RogerBlack]

I am unsure if I've seen anything else going into the time to recover after exercise. Very welcome.

 

[daisybell]

Hoping I might be able to take part in this research.....!

 

[Mesurfer]

We need more research like this. I don't understand with huge findings like this we are still virtually being ignored. I just don't get it...

 

[Lolo]

Brave souls volunteering for that! Four weeks to recover. I hope they don't repeat this experiment too often. Move forward please!

 

[*GG*]

Press release from New Zealand providing more confirmation of two-day Cardiopulmonary Exercise Testing (CPET) abnormalities in those with ME/CFS:

http://www.scoop.co.nz/stories/GE1705/S00067/distinguishing-chronic-fatigue-syndrome.htm

"Dr Lynette Hodges from Massey University’s School of Sport and Exercise recently conducted a study comparing the physiological responses of CFS/ME, Multiple Sclerosis (MS) and healthy controls following a repeated maximal exercise test."

“On the second exercise test, those with MS and those who were healthy were able to repeat the same results on the exercise as on day one. However, those with CFS/ME were unable to achieve this and reached their anaerobic threshold faster and at a lower workload compared to day one,”

“Our study also showed that some individuals with CFS/ME took up to four weeks to recover following the two exercise tests, which was not apparent in the healthy individuals who were back to normal the following day.”

Here are the results of my testing almost 7 years ago, 14 years ill now.

GG

 

[ahmo]

I'm always surprised at how many days it takes me to recover from nothing much. Great to see this validation and the ongoing research.

 

[Lolo]

I'm always surprised at how many days it takes me to recover from nothing much

I am no longer surprised.

 

[Hutan]

Dr Hodges found that on the first test, there was no difference between healthy controls and CFS/ME. The first exercise test also showed that those with MS were significantly less fit than those who were healthy and compared to those with CFS/ME.

“On the second exercise test, those with MS and those who were healthy were able to repeat the same results on the exercise as on day one. However, those with CFS/ME were unable to achieve this and reached their anaerobic threshold faster and at a lower workload compared to day one,” Dr Hodges says.

“This suggests that even though they were as fit as the healthy controls, post-exertional malaise [the feeling of fatigue] after exercise, shows up by them not being able to achieve the same workload at anaerobic threshold or at their peak.”

Obviously these were people fairly mildly affected by ME/CFS. But it does make the idea that:
ME/CFS = fear of exercise + deconditioning
look pretty baseless.

So good to see useful research. I look forward to the published paper and news of the planned research.

 

[Diwi9]

Just want to back up what @Lolo said. PWME that subject themselves to these studies are knowingly doing so at their own peril. @Hutan - so right...clearly not "fear of exercise"...!!!

 

[Lolo]

PWME that subject themselves to these studies are knowingly doing so at their own peril.

If they didn't know before they will now.

 

[Snow Leopard]

I am unsure if I've seen anything else going into the time to recover after exercise. Very welcome.

The 2-day CPET/maximal exercise test is very difficult, most people who have done it (myself included) took 3-4 weeks to recover.

My own experience on the second day is that it wasn't that I felt puffed out at all, the inability to hit the same VO2Max/power level is that my legs physically felt weaker the whole time and maxed out sooner.

 

[Gijs]

Where is the publication?

 

[shannah]

I don't see the criteria that was used.

 

[slysaint]

"To find out more, Dr Hodges is completing another trial examining the physiological differences in repeated maximal exercise at 48 hours and 72 hours. “We will be taking blood samples to examine markers of inflammation, blood pressure and heart rate, asking questions about fatigue, and participants will be asked to do simple computer tasks to examine cognition, as well as ultrasound to measure arterial stiffness, and the cycle test to examine anaerobic threshold. All tests will then be repeated at either 48 hours or 72 hours later.”

shame all the other 'exercise trials' didn't do anything like this years ago; we could be a lot further forward by now.

 

[shannah]

Where is the publication?

"The outcomes of the study will soon be published in the Journal of Clinical Physiology and Functional Imaging."

@Gijs

 

[Snow Leopard]

It doesn't seem to be online yet.
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-097X

http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-097X/earlyview

 

[lauluce]

I took the 48hs CPET and my result where as they are described in the article

 

[A.B.]

Hopefully Ron can soon offer a CPET for cells in a chip.